Organization profile
Organization profile
Ion channels are molecules that are expressed in excitable and non-excitable cells, where they fulfill functions related to the transduction of sensory stimuli, proliferation, differentiation, among other processes and whose alteration is related to the development of various pathologies.This research hotbed is focused on the study of the functional and structural aspects of BK-type channels and TRP family channels.BK channels are of great importance given their ability to integrate electrical signals and intracellular signaling.For their part, TRP channels are associated with thermal sensation and the transduction of pain stimuli.
Research fields
The projects developed in the line of research in Ion Channels are framed in the following areas: Determination of the role of BK and TRP channels in cellular alterations related to obstructive sleep apnea;Study of ion channels of the TRP family as molecular targets for the treatment of chronic pain;Role of TRP channels in the physiology of mesenchymal cells.
Organization profile
Ion channels are molecules that are expressed in excitable and non-excitable cells, where they fulfill functions related to the transduction of sensory stimuli, proliferation, differentiation, among other processes and whose alteration is related to the development of various pathologies.This research hotbed is focused on the study of the functional and structural aspects of BK-type channels and TRP family channels.BK channels are of great importance given their ability to integrate electrical signals and intracellular signaling.For their part, TRP channels are associated with thermal sensation and the transduction of pain stimuli.
Área de conocimiento (OCDE)
- Natural Sciences
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Zulma Yanira Casas Corredor
- Department of Nutrition and Biochemistry - Assistant Professor
- Experimental and Computational Biochemistry - Member research group
- Biophysics and physiology of ionic channels. - Co-tutor Research Student Group
Person: Academic, Researcher, Tutor
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Yolima Del Pilar Torres Ruiz
- Department of Nutrition and Biochemistry - Full Professor
- Experimental and Computational Biochemistry - Member research group
- Biophysics and physiology of ionic channels. - Tutor Research Student Group
Person: Academic, Researcher, Tutor
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Therapeutic potential of TRPM8 channels in cancer treatment
Ochoa, S. V., Casas, Z., Albarracín, S. L., Sutachan, J. J. & Torres, Y. P., 2023, In: Frontiers in Pharmacology. 14, 1098448.Research output: Contribution to journal › Review article › peer-review
29 Scopus citations -
Trp channels as molecular targets to relieve cancer pain
Duitama, M., Moreno, Y., Santander, S. P., Casas, Z., Sutachan, J. J., Torres, Y. P. & Albarracín, S. L., Jan 2022, In: Biomolecules. 12, 1, 1.Research output: Contribution to journal › Review article › peer-review
45 Scopus citations -
Hypoxic Regulation of the Large-Conductance, Calcium and Voltage-Activated Potassium Channel, BK
Ochoa, S. V., Otero, L., Aristizabal-Pachon, A. F., Hinostroza, F., Carvacho, I. & Torres, Y. P., 22 Dec 2021, In: Frontiers in Physiology. 12, 780206.Research output: Contribution to journal › Review article › peer-review
24 Scopus citations
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Nuevas perspectivas en la exploración del mecanismo de interacción de estatinas con canales de calcio dependientes de voltaje expresados en músculo liso vascular
Torres Ruiz, Y. D. P. (PI), Casas Corredor, Z. Y. (CoI) & Otero Mendoza, L. M. (CoI)
01/10/25 → 30/04/27
Project: Research
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Generación de una línea celular estable en células HEK293, como modelo celular para el estudio de la actividad de canales BK.
Daza Moreno, J. S. (Estud), Rincón Manzanares, P. N. (Estud) & Torres Ruiz, Y. D. P. (Tut)
02/09/24 → 01/03/26
Project: Research
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Análisis de la actividad de canales TRPV1 en leucocitos aislados de sangre periférica de pacientes con apnea obstructiva del sueño
Torres Ruiz, Y. D. P. (PI), Aristizábal Pachon, A. F. (CoI), Carvacho, I. (CoI), Otero Mendoza, L. M. (CoI), Millan Perez, S. P. (Ases) & Saltos Cristiano, M. (Ases)
04/11/22 → 04/07/25
Project: Research