TY - JOUR
T1 - Metabolically Unhealthy Normal Weight
T2 - Prevalence and Associated Factors in an Adult Population from Northwest Colombia
AU - López-Herrera, Julián Andrés
AU - Castillo, Adriana Nathaly
AU - Ordoñez-Betancourth, Jenny Elizabeth
AU - de Jesús Martínez Quiroz, Wilson
AU - Higuita-Gutiérrez, Luis Felipe
AU - Suarez-Ortegon, Milton F.
N1 - Publisher Copyright:
© 2024 López-Herrera et al.
PY - 2024
Y1 - 2024
N2 - Background and Aim: Individuals with a normal weight may have metabolic alterations at risk for chronic non-communicable diseases. The prevalence of this condition and associated factors have not been reported in Latin American populations. We aimed to estimate the presence and associated factors of Metabolically Unhealthy Normal Weight (MUNW) in adults from a public program for the control and prevention of chronic diseases in Medellín, Colombia. Methods: Cross-sectional study. Overweight and normal weight were characterized according to the absence or presence of one or more components of the metabolic syndrome, obtaining four phenotypes: Metabolically Healthy Normal Weight (MHNW), MUNW (phenotype of interest), Metabolically Healthy Overweight (MHO), and Metabolically Unhealthy Overweight (MUO). The association of these phenotypes with sociodemographic variables of lifestyles and increased waist circumference was conducted by using logistic regression. Results: In 37,558 individuals (72.7% women), the prevalence of MUNW was 23.3%. Among the additional phenotypes, MUO was found to be more prevalent (71.6%), while MHNW and MHO were very slightly common, 2% and 3.1%, respectively. In a multiple model, the factors associated with MUNW were age over 60 years (trend [OR 1.56 95% CI 0.97–2.52] p-value = 0.066), living in a rural area ([OR 1.58 95% CI 1.09–2.29] p-value = 0.015), and increased waist circumference ([OR 1.68 95% CI 1.45–1.95] p-value < 0.001). Male gender was inversely associated with all phenotypes (P < 0.05). Conclusion: Almost a quarter of the analyzed population presented MUNW. People living in a rural area and over 60 years old were more likely to present MUNW. Men were less likely to present the weight phenotypes studied, although they could have been underrepresented.
AB - Background and Aim: Individuals with a normal weight may have metabolic alterations at risk for chronic non-communicable diseases. The prevalence of this condition and associated factors have not been reported in Latin American populations. We aimed to estimate the presence and associated factors of Metabolically Unhealthy Normal Weight (MUNW) in adults from a public program for the control and prevention of chronic diseases in Medellín, Colombia. Methods: Cross-sectional study. Overweight and normal weight were characterized according to the absence or presence of one or more components of the metabolic syndrome, obtaining four phenotypes: Metabolically Healthy Normal Weight (MHNW), MUNW (phenotype of interest), Metabolically Healthy Overweight (MHO), and Metabolically Unhealthy Overweight (MUO). The association of these phenotypes with sociodemographic variables of lifestyles and increased waist circumference was conducted by using logistic regression. Results: In 37,558 individuals (72.7% women), the prevalence of MUNW was 23.3%. Among the additional phenotypes, MUO was found to be more prevalent (71.6%), while MHNW and MHO were very slightly common, 2% and 3.1%, respectively. In a multiple model, the factors associated with MUNW were age over 60 years (trend [OR 1.56 95% CI 0.97–2.52] p-value = 0.066), living in a rural area ([OR 1.58 95% CI 1.09–2.29] p-value = 0.015), and increased waist circumference ([OR 1.68 95% CI 1.45–1.95] p-value < 0.001). Male gender was inversely associated with all phenotypes (P < 0.05). Conclusion: Almost a quarter of the analyzed population presented MUNW. People living in a rural area and over 60 years old were more likely to present MUNW. Men were less likely to present the weight phenotypes studied, although they could have been underrepresented.
KW - body mass index
KW - metabolic profile
KW - metabolic syndrome
KW - metabolism
KW - normal weight
KW - risk factor
UR - http://www.scopus.com/inward/record.url?scp=85188278488&partnerID=8YFLogxK
U2 - 10.2147/DMSO.S449213
DO - 10.2147/DMSO.S449213
M3 - Article
AN - SCOPUS:85188278488
SN - 1178-7007
VL - 17
SP - 1337
EP - 1357
JO - Diabetes, Metabolic Syndrome and Obesity
JF - Diabetes, Metabolic Syndrome and Obesity
ER -