Resumen
Background: Systemic sclerosis (SSc) is a rare autoimmune disease with diverse clinical presentations and a high disease burden. Registries have allowed a better understanding of the disease. However, research in Latin America is scarce, and registries are lacking.Methods: We present the Colombian Consortium for the Development of Research on
Systemic Sclerosis (CCONDORSS) institutional registry. Based on the preliminary data
retrieved, we conducted an observational, descriptive, longitudinal study with a one-year follow-up.
Results: This preliminary analysis included 44 confirmed SSc patients (95.4% women), with a median follow-up of 379 days (IQR, 331–420). The median age at diagnosis was 58 years; 86.4% had limited cutaneous disease. At baseline, interstitial lung disease was present in 18.2%, pulmonary arterial hypertension in 11.4%, and gastrointestinal/musculoskeletal involvement was common; digital ulcers and calcinosis were rare. During follow-up, 50% (7/14) of VEDOSS patients progressed to SSc. Methotrexate and calcium-channel blockers were the most used medications (>70%). No major complications or deaths occurred.
Conclusion: The CCONDORSS registry lays the groundwork for future multicenter
collaboration and epidemiological characterization of SSc in Colombia, supporting future research and care strategies.
| Fecha de lectura | 2025 |
|---|---|
| Idioma original | Inglés |
| Institución de lectura |
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| Supervisor | Santiago Bernal Macias (Director) |