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Keyphrases
GM2 Ganglioside
100%
β-hexosaminidase
100%
Recombinant
100%
Tay-Sachs Disease
100%
Lysosome-associated Membrane Protein 1 (LAMP1)
50%
Hexosaminidase A
33%
Colocalization
33%
Fibroblast Cells
33%
Neuroglial Cells
33%
Effective Treatment
16%
Lysosomal Storage Disease
16%
Metabolism
16%
Lysosomal Accumulation
16%
Murine Model
16%
Enzyme Replacement Therapy
16%
Mouse Model
16%
Fibroblasts
16%
Lysosome
16%
Pichia Pastoris
16%
Lipids
16%
Neural Stem Cells
16%
Neuropathology
16%
Regulatory Interactions
16%
Autosomal Recessive
16%
Premature Death
16%
Methylotrophic Yeast
16%
HEXB Gene
16%
HEXA Gene
16%
Induced Pluripotent Stem Cells (iPSCs)
16%
GM2AP
16%
LysoTracker
16%
Stem Cell-derived
16%
LysoTracker Red
16%
Immunofluorescence Staining
16%
Metabolic Pathways
16%
INIS
humans
100%
diseases
100%
accumulation
100%
yeasts
100%
gangliosides
100%
levels
50%
patients
50%
fibroblasts
50%
genes
33%
enzymes
33%
stem cells
33%
interactions
16%
death
16%
metabolism
16%
investigations
16%
mutations
16%
therapy
16%
storage
16%
mice
16%
membrane proteins
16%
lipids
16%
lysosomes
16%
metabolic pathways
16%
Biochemistry, Genetics and Molecular Biology
Hexosaminidase
100%
GM2 (Ganglioside)
100%
Tay-Sachs Disease
100%
Fibroblast
50%
Metabolic Pathway
33%
Enzyme
33%
Staining
33%
Microglia
33%
Colocalization
33%
Immunofluorescence
16%
HEXA
16%
Lysosome
16%
Stem Cell
16%
Recombinant
16%
Mouse Model
16%
Komagataella pastoris
16%
Autosomal Recessive Inheritance
16%
Methylotrophic Yeast
16%
Synapsin I
16%
Induced Pluripotent Stem Cell
16%
Internalization
16%
Neuroglia
16%
LAMP1
16%
Lipid
16%