Tuberculous pericarditis-a silent and challenging disease: A case report

Oscar David Lucero Pantoja; Marlon Mauricio Bustos Claro; Darwin Jhoan Ariza-Rodríguez; Juan Camilo Pérez-Correa

doi:10.12998/wjcc.v10.i6.1869

Tuberculous pericarditis-a silent and challenging disease: A case report

Oscar David Lucero Pantoja
, Marlon Mauricio Bustos Claro
, Darwin Jhoan Ariza-Rodríguez
, Juan Camilo Pérez-Correa

Hospital Universitario San Ignacio
Pontificia Universidad Javeriana

Producción: Contribución a una revista › Artículo › revisión exhaustiva

8 Citas (Scopus)

Resumen

A 49-year-old woman presented with dyspnea, chest pain and dry cough. On
physical examination, veiled heart sounds were found. The electrocardiogram
showed low-voltage complexes and the transthoracic echocardiography revealed
a large and free-looking pericardial effusion. The patient was taken for an open
pericardiotomy. The pericardial fluid revealed high levels of adenosine deaminase
and Ziehl-Neelsen stain showed acid-fast bacilli. Polymerase chain reaction study
for Mycobacterium tuberculosis in pericardial fluid was positive. The patient
received tetra conjugate management with adequate clinical response after the
first week of treatment and resolution of fever and chest pain.

Idioma original	Inglés
Páginas (desde-hasta)	1869-1875
Número de páginas	7
Publicación	World Journal of Clinical Cases
Volumen	10
N.º	6
DOI	https://doi.org/10.12998/wjcc.v10.i6.1869
Estado	Publicada - 26 feb. 2022

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

ODS 3: Salud y bienestar
ODS 4: Educación de calidad

Palabras clave

Tuberculosis; Pericardial disease; Tuberculous pericarditis; Pericardial effusion; Mycobacterium tuberculosis; Case report

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@article{1eb4c5e552c94b26a530a56acc334204,

title = "Tuberculous pericarditis-a silent and challenging disease: A case report",

abstract = "BACKGROUND Tuberculous pericarditis (TP) remains a challenge for endemic countries. In developing countries, one to two percent of patients with pulmonary tuberculosis develops TP. CASE SUMMARY A 49-year-old woman presented with dyspnea, chest pain and dry cough. On physical examination, veiled heart sounds were found. The electrocardiogram showed low-voltage complexes and the transthoracic echocardiography revealed a large and free-looking pericardial effusion. The patient was taken for an open pericardiotomy. The pericardial fluid revealed high levels of adenosine deaminase and Ziehl-Neelsen stain showed acid-fast bacilli. Polymerase chain reaction study for Mycobacterium tuberculosis in pericardial fluid was positive. The patient received tetra conjugate management with adequate clinical response after the first week of treatment and resolution of fever and chest pain. CONCLUSION In cases of TP, obtaining pericardial fluid and/or pericardial biopsy is the most efficient strategy to confirm the diagnosis. Early diagnosis of this entity will allow physicians to initiate timely treatment, avoid complications and improve the patient's clinical outcome, so we consider the description of this case pertinent and its review in the literature.",

keywords = "Tuberculosis; Pericardial disease; Tuberculous pericarditis; Pericardial effusion; Mycobacterium tuberculosis; Case report, Tuberculosis, Pericardial disease, Tuberculous pericarditis, Pericardial effusion, Mycobacterium tuberculosis",

author = "\{Lucero Pantoja\}, \{Oscar David\} and \{Bustos Claro\}, \{Marlon Mauricio\} and Ariza-Rodr{\'i}guez, \{Darwin Jhoan\} and P{\'e}rez-Correa, \{Juan Camilo\}",

year = "2022",

month = feb,

day = "26",

doi = "10.12998/wjcc.v10.i6.1869",

language = "English",

volume = "10",

pages = "1869--1875",

journal = "World Journal of Clinical Cases",

issn = "2307-8960",

publisher = "Baishideng Publishing Group Inc",

number = "6",

}

TY - JOUR

T1 - Tuberculous pericarditis-a silent and challenging disease

T2 - A case report

AU - Lucero Pantoja, Oscar David

AU - Bustos Claro, Marlon Mauricio

AU - Ariza-Rodríguez, Darwin Jhoan

AU - Pérez-Correa, Juan Camilo

PY - 2022/2/26

Y1 - 2022/2/26

N2 - BACKGROUND Tuberculous pericarditis (TP) remains a challenge for endemic countries. In developing countries, one to two percent of patients with pulmonary tuberculosis develops TP. CASE SUMMARY A 49-year-old woman presented with dyspnea, chest pain and dry cough. On physical examination, veiled heart sounds were found. The electrocardiogram showed low-voltage complexes and the transthoracic echocardiography revealed a large and free-looking pericardial effusion. The patient was taken for an open pericardiotomy. The pericardial fluid revealed high levels of adenosine deaminase and Ziehl-Neelsen stain showed acid-fast bacilli. Polymerase chain reaction study for Mycobacterium tuberculosis in pericardial fluid was positive. The patient received tetra conjugate management with adequate clinical response after the first week of treatment and resolution of fever and chest pain. CONCLUSION In cases of TP, obtaining pericardial fluid and/or pericardial biopsy is the most efficient strategy to confirm the diagnosis. Early diagnosis of this entity will allow physicians to initiate timely treatment, avoid complications and improve the patient's clinical outcome, so we consider the description of this case pertinent and its review in the literature.

AB - BACKGROUND Tuberculous pericarditis (TP) remains a challenge for endemic countries. In developing countries, one to two percent of patients with pulmonary tuberculosis develops TP. CASE SUMMARY A 49-year-old woman presented with dyspnea, chest pain and dry cough. On physical examination, veiled heart sounds were found. The electrocardiogram showed low-voltage complexes and the transthoracic echocardiography revealed a large and free-looking pericardial effusion. The patient was taken for an open pericardiotomy. The pericardial fluid revealed high levels of adenosine deaminase and Ziehl-Neelsen stain showed acid-fast bacilli. Polymerase chain reaction study for Mycobacterium tuberculosis in pericardial fluid was positive. The patient received tetra conjugate management with adequate clinical response after the first week of treatment and resolution of fever and chest pain. CONCLUSION In cases of TP, obtaining pericardial fluid and/or pericardial biopsy is the most efficient strategy to confirm the diagnosis. Early diagnosis of this entity will allow physicians to initiate timely treatment, avoid complications and improve the patient's clinical outcome, so we consider the description of this case pertinent and its review in the literature.

KW - Tuberculosis; Pericardial disease; Tuberculous pericarditis; Pericardial effusion; Mycobacterium tuberculosis; Case report

KW - Tuberculosis

KW - Pericardial disease

KW - Tuberculous pericarditis

KW - Pericardial effusion

KW - Mycobacterium tuberculosis

UR - https://www.wjgnet.com/2307-8960/full/v10/i6/1869.htm

U2 - 10.12998/wjcc.v10.i6.1869

DO - 10.12998/wjcc.v10.i6.1869

M3 - Article

SN - 2307-8960

VL - 10

SP - 1869

EP - 1875

JO - World Journal of Clinical Cases

JF - World Journal of Clinical Cases

IS - 6

ER -

Tuberculous pericarditis-a silent and challenging disease: A case report

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