Thyroid storm: Diagnostic and therapeutic approach

José Correa-Guerrero; Hugo Corrales Santander; Jorge Yepes Caro; Jesús Bello Simanca; Luis Rodríguez Arrieta; Alejandro Castellanos Pinedo; Elguis Rodríguez Garizabalo; Carmelo Dueñas Castell

doi:10.1016/j.acci.2024.10.010

Thyroid storm: Diagnostic and therapeutic approach

Título traducido de la contribución: Tormenta tiroidea: abordaje diagnóstico y terapéutico

José Correa-Guerrero
, Hugo Corrales Santander
, Jorge Yepes Caro
, Jesús Bello Simanca
, Luis Rodríguez Arrieta
, Alejandro Castellanos Pinedo
, Elguis Rodríguez Garizabalo
, Carmelo Dueñas Castell

Universidad de Cartagena
Universidad Nacional de Colombia
Universidad de Antioquia
Hospital San Jerónimo de Montería
Universidad Simón Bolívar

Producción: Contribución a una revista › Artículo de revisión › revisión exhaustiva

Resumen

Thyroid storm (TT) is a rare but potentially fatal condition if not detected and treated promptly. It is characterized by severe clinical manifestations at the level of the central nervous system, cardiovascular system, and gastrointestinal system, associated with elevated levels of free triiodothyronine (T3) and free thyroxine (T4). Infections and/or treatment discontinuation are the most frequent triggers. Identifying the triggering factor, reducing circulating levels of thyroid hormones, and admission to an intensive care unit become the cornerstone of treatment. In this review, based on a clinical scenario, we will provide information regarding the diagnostic and therapeutic approach to TT.

Título traducido de la contribución	Tormenta tiroidea: abordaje diagnóstico y terapéutico
Idioma original	Inglés
Páginas (desde-hasta)	159-173
Número de páginas	15
Publicación	Acta Colombiana de Cuidado Intensivo
Volumen	25
N.º	1
DOI	https://doi.org/10.1016/j.acci.2024.10.010
Estado	Publicada - 01 ene 2025
Publicado de forma externa	Sí

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10.1016/j.acci.2024.10.010

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title = "Thyroid storm: Diagnostic and therapeutic approach",

abstract = "Thyroid storm (TT) is a rare but potentially fatal condition if not detected and treated promptly. It is characterized by severe clinical manifestations at the level of the central nervous system, cardiovascular system, and gastrointestinal system, associated with elevated levels of free triiodothyronine (T3) and free thyroxine (T4). Infections and/or treatment discontinuation are the most frequent triggers. Identifying the triggering factor, reducing circulating levels of thyroid hormones, and admission to an intensive care unit become the cornerstone of treatment. In this review, based on a clinical scenario, we will provide information regarding the diagnostic and therapeutic approach to TT.",

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T2 - Diagnostic and therapeutic approach

AU - Correa-Guerrero, José

AU - Corrales Santander, Hugo

AU - Yepes Caro, Jorge

AU - Bello Simanca, Jesús

AU - Rodríguez Arrieta, Luis

AU - Castellanos Pinedo, Alejandro

AU - Rodríguez Garizabalo, Elguis

AU - Dueñas Castell, Carmelo

PY - 2025/1/1

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N2 - Thyroid storm (TT) is a rare but potentially fatal condition if not detected and treated promptly. It is characterized by severe clinical manifestations at the level of the central nervous system, cardiovascular system, and gastrointestinal system, associated with elevated levels of free triiodothyronine (T3) and free thyroxine (T4). Infections and/or treatment discontinuation are the most frequent triggers. Identifying the triggering factor, reducing circulating levels of thyroid hormones, and admission to an intensive care unit become the cornerstone of treatment. In this review, based on a clinical scenario, we will provide information regarding the diagnostic and therapeutic approach to TT.

AB - Thyroid storm (TT) is a rare but potentially fatal condition if not detected and treated promptly. It is characterized by severe clinical manifestations at the level of the central nervous system, cardiovascular system, and gastrointestinal system, associated with elevated levels of free triiodothyronine (T3) and free thyroxine (T4). Infections and/or treatment discontinuation are the most frequent triggers. Identifying the triggering factor, reducing circulating levels of thyroid hormones, and admission to an intensive care unit become the cornerstone of treatment. In this review, based on a clinical scenario, we will provide information regarding the diagnostic and therapeutic approach to TT.

KW - Antithyroid therapy

KW - Endocrine emergency

KW - Hyperthyroidism

KW - Multiorgan dysfunction

KW - Thyroid storm

KW - Thyrotoxicosis

UR - https://www.scopus.com/pages/publications/85210299969

U2 - 10.1016/j.acci.2024.10.010

DO - 10.1016/j.acci.2024.10.010

M3 - Review article

AN - SCOPUS:86000426653

SN - 0122-7262

VL - 25

SP - 159

EP - 173

JO - Acta Colombiana de Cuidado Intensivo

JF - Acta Colombiana de Cuidado Intensivo

IS - 1

ER -

Thyroid storm: Diagnostic and therapeutic approach

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