Thymic Squamous Cell Carcinoma and Brain Metastases: Case Report and Literature Review

Thymic squamous cell carcinoma (TSCC) is a rare cancer that is typically characterized by low rates of brain metastases. However, when it does occur, brain metastases of TSCC can have significant clinical implications due to its rarity and lack of established management guidelines. In this literature review and case report, we explore the clinical presentation, management, and outcomes of patients with brain metastases of TSCC. Our literature review found that brain metastases of TSCC are relatively rare, with an estimated incidence of 5-10 % among patients with advanced-stage disease. Management of brain metastases of TSCC often involves a combination of surgical resection, radiation therapy, and chemotherapy. However, due to the rarity of this condition, there is currently limited evidence to guide optimal treatment strategies. We also present a case report of a patient with TSCC who was presented with a brain metastasis. This case highlights the importance of early diagnosis and prompt management of brain metastasis of TSCC to improve patient outcomes. Our review and case report underscore the need for further research to improve our understanding of the clinical characteristics, optimal management, and prognosis of patients with brain metastasis of TSCC.