TY - PAT
T1 - SYNTHETIC OLIGOPEPTIDES DESIGNED FROM MITE CYSTEINE PROTEASES AND METHODS FOR THE PRODUCTION OF IGY POLYCLONAL ANTIBODIES FOR THE DETECTION OF INTRADOMICILIARY MITES
AU - Egea, Eduardo
AU - Barrera Avellaneda, Luis Alejandro
AU - Espejo Mojica, Angela Johana
AU - Sosa Molano, Angela Catalina
AU - Navarro, Elkin
AU - Garavito, Gloria
AU - Mendoza, Luz Dary
PY - 2015/8/5
Y1 - 2015/8/5
N2 - The invention refers to the design, synthesis and evaluation of 6 synthetic oligopeptides, that have not been previously described, designed from the T and B epitopes of allergens of group I of intradomiciliary mites of the species Dermatophagoides pteronyssinus, Dermatophagoides farinae and Blomia tropicalis, which can be used in the immunomodulation of individuals having immunocompetent systems and in the production of IgY polyclonal antibodies. The invention relates to a first method for obtaining a composition of IgY polyclonal antibodies that can be used as a diagnostic reagent having low cost and high reactivity in respect of intradomiciliary mites, and a second method for the detection of mite allergens, using the IgY antibody composition developed in the first method. The invention further relates to the composition of the IgY polyclonal antibodies.
AB - The invention refers to the design, synthesis and evaluation of 6 synthetic oligopeptides, that have not been previously described, designed from the T and B epitopes of allergens of group I of intradomiciliary mites of the species Dermatophagoides pteronyssinus, Dermatophagoides farinae and Blomia tropicalis, which can be used in the immunomodulation of individuals having immunocompetent systems and in the production of IgY polyclonal antibodies. The invention relates to a first method for obtaining a composition of IgY polyclonal antibodies that can be used as a diagnostic reagent having low cost and high reactivity in respect of intradomiciliary mites, and a second method for the detection of mite allergens, using the IgY antibody composition developed in the first method. The invention further relates to the composition of the IgY polyclonal antibodies.
UR - https://worldwide.espacenet.com/patent/search/family/043356819/publication/EP2431381A2?q=EP2431381
M3 - Invention patent
M1 - EP2431381
Y2 - 2011/09/19
ER -