Murine model of rotavirus infection

Ningguo Feng, Manuel A. Franco, Harry B. Greenberg

Producción: Contribución a una revistaArtículorevisión exhaustiva

27 Citas (Scopus)

Resumen

The murine model of homologous rotavirus infection has been used to study the determinants of protection. The local IgA immune response appears to be the critical factor in generating protective immunity after natural infection. A series of knockout mice were used to evaluate the contribution of T cells and B cells to immunity and resolution from primary infection. Both arms of immune system played a role in the resolution of primary infection but antibody was much more important for prevention of reinfection.

Idioma originalInglés
Páginas (desde-hasta)233-240
Número de páginas8
PublicaciónAdvances in Experimental Medicine and Biology
Volumen412
DOI
EstadoPublicada - 1997
Publicado de forma externa

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