Leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus

Diana Nathalie Rincón-Riaño; Daniel G. Fernández-Ávila; Juan M. Gutiérrez

doi:10.1016/j.rcreu.2017.05.003

Leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus

Título traducido de la contribución: Síndrome de Stevens Johnson inducido por leflunomida en un paciente con lupus eritematoso sistémico

Diana Nathalie Rincón-Riaño, Daniel G. Fernández-Ávila, Juan M. Gutiérrez

Hospital Universitario San Ignacio

Producción: Contribución a una revista › Artículo › revisión exhaustiva

1 Cita (Scopus)

Resumen

Leflunomide is an immunomodulatory agent widely used in rheumatoid arthritis and other rheumatic diseases like psoriatic arthritis and systemic lupus erythematosus. Although its safety profile is generally good, side effects have been reported in up to 20% of cases. Severe reactions, such as toxic epidermal necrolysis and Stevens Johnson syndrome are rare. The case is presented of a leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus.

Título traducido de la contribución	Síndrome de Stevens Johnson inducido por leflunomida en un paciente con lupus eritematoso sistémico
Idioma original	Inglés
Páginas (desde-hasta)	242-246
Número de páginas	5
Publicación	Revista Colombiana de Reumatologia
Volumen	24
N.º	4
DOI	https://doi.org/10.1016/j.rcreu.2017.05.003
Estado	Publicada - oct. 2017
Publicado de forma externa	Sí

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title = "Leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus",

abstract = "Leflunomide is an immunomodulatory agent widely used in rheumatoid arthritis and other rheumatic diseases like psoriatic arthritis and systemic lupus erythematosus. Although its safety profile is generally good, side effects have been reported in up to 20% of cases. Severe reactions, such as toxic epidermal necrolysis and Stevens Johnson syndrome are rare. The case is presented of a leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus.",

keywords = "Adverse effects, Leflunomide, Stevens-Johnson syndrome",

author = "Rinc{\'o}n-Ria{\~n}o, {Diana Nathalie} and Fern{\'a}ndez-{\'A}vila, {Daniel G.} and Guti{\'e}rrez, {Juan M.}",

note = "Publisher Copyright: {\textcopyright} 2017 Asociaci{\'o}n Colombiana de Reumatolog{\'i}a",

year = "2017",

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doi = "10.1016/j.rcreu.2017.05.003",

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AU - Rincón-Riaño, Diana Nathalie

AU - Fernández-Ávila, Daniel G.

AU - Gutiérrez, Juan M.

PY - 2017/10

Y1 - 2017/10

N2 - Leflunomide is an immunomodulatory agent widely used in rheumatoid arthritis and other rheumatic diseases like psoriatic arthritis and systemic lupus erythematosus. Although its safety profile is generally good, side effects have been reported in up to 20% of cases. Severe reactions, such as toxic epidermal necrolysis and Stevens Johnson syndrome are rare. The case is presented of a leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus.

AB - Leflunomide is an immunomodulatory agent widely used in rheumatoid arthritis and other rheumatic diseases like psoriatic arthritis and systemic lupus erythematosus. Although its safety profile is generally good, side effects have been reported in up to 20% of cases. Severe reactions, such as toxic epidermal necrolysis and Stevens Johnson syndrome are rare. The case is presented of a leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus.

KW - Adverse effects

KW - Leflunomide

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DO - 10.1016/j.rcreu.2017.05.003

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JO - Revista Colombiana de Reumatologia

JF - Revista Colombiana de Reumatologia

IS - 4

ER -

Leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus

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