TY - JOUR
T1 - Interpretación de pruebas genéticas y biomarcadores en la distrofia muscular de Duchenne
AU - Huertas-Quiñones, Manuel
AU - Suárez-Obando, Fernando
AU - Barajas-Viracachá, Norma Carolina
AU - Becerra-Ortiz, Paulo César
AU - Bobadilla-Quesada, Edna Julieth
AU - Bolaños-Almeida, Carlos Ernesto
AU - Cañón-Zambrano, José Manuel
AU - Castellar-Leones, Sandra Milena
AU - Jurado-Hernández, Jenny Libeth
AU - Lasprilla-Tovar, Juan David
AU - Laza-Gutiérrez, Nicolás J.
AU - Londoño Ossa, Isabel C.
AU - Ortiz-Giraldo, Blair
AU - Ortiz-Corredor, Fernando
AU - Ospina-Lagos, Sandra Janeth
AU - Prieto, Juan Carlos
AU - Rivera-Nieto, Carolina
AU - Ruiz-Ospina, Edicson
AU - Ruiz-Botero, Felipe
AU - Salcedo-Maldonado, María Claudia
AU - Soto-Peña, Diana Pilar
AU - Tavera-Saldaña, Lina Marcela
AU - Torres-Nieto, María Julia
AU - Sánchez-Peñarete, Diana Carolina
N1 - Publisher Copyright:
© 2025, Universidad del Rosario. All rights reserved.
PY - 2025/4/22
Y1 - 2025/4/22
N2 - Among the main characteristics of Duchenne muscular dystrophy (dmd) are the damage of muscle fibers during contraction, subsequent chronic muscle damage, inflammation, and subsequent replacement of muscle fibers by fibrous tissue. Biomarkers of the disease can reflect these types of alterations. Biomarkers in dmd are helpful for diagnosis, follow-up, and evaluation of the response to treatment. The indication for requesting different biomarkers varies according to the age and natural history of the disease, and their correct use allows for an adequate therapeutic approach, correct follow-up, and successful rehabilitation. The present review describes the different types of biomarkers and diagnostic methods used in patients with dmd and recommends their appropriate use according to their age and natural history of the disease.
AB - Among the main characteristics of Duchenne muscular dystrophy (dmd) are the damage of muscle fibers during contraction, subsequent chronic muscle damage, inflammation, and subsequent replacement of muscle fibers by fibrous tissue. Biomarkers of the disease can reflect these types of alterations. Biomarkers in dmd are helpful for diagnosis, follow-up, and evaluation of the response to treatment. The indication for requesting different biomarkers varies according to the age and natural history of the disease, and their correct use allows for an adequate therapeutic approach, correct follow-up, and successful rehabilitation. The present review describes the different types of biomarkers and diagnostic methods used in patients with dmd and recommends their appropriate use according to their age and natural history of the disease.
KW - Duchenne muscular dystrophy
KW - biomarkers
KW - genetic testing
UR - https://www.scopus.com/pages/publications/105005470924
U2 - 10.12804/revistas.urosario.edu.co/revsalud/a.13656
DO - 10.12804/revistas.urosario.edu.co/revsalud/a.13656
M3 - Artículo
AN - SCOPUS:105005470924
SN - 1692-7273
VL - 23
JO - Revista Ciencias de la Salud
JF - Revista Ciencias de la Salud
ER -