High prevalence of pulmonary tuberculosis in the indigenous population of Puerto Nariño, Colombian Amazonia

Clara V. Mape; Alejandro Vega; Sonia Valencia; Francy Pérez-Llanos; Carlos Parra-López; Ricardo Sánchez; Myriam Navarrete; Martha I. Murcia

doi:10.15446/rsap.v27n1.117145

High prevalence of pulmonary tuberculosis in the indigenous population of Puerto Nariño, Colombian Amazonia

Título traducido de la contribución: Alta prevalencia de tuberculosis pulmonar en la población indígena de Puerto Nariño, Amazonía de Colombia

Clara V. Mape, Alejandro Vega, Sonia Valencia, Francy Pérez-Llanos, Carlos Parra-López, Ricardo Sánchez, Myriam Navarrete, Martha I. Murcia

Universidad Nacional de Colombia

Producción: Contribución a una revista › Artículo › revisión exhaustiva

Resumen

a tuberculosis (tb) sigue siendo un importante desafío en la salud pública, que afecta de manera desproporcionada a los grupos vulnerables, en especial a los pueblos indígenas. Objetivo Investigar el comportamiento epidemiológico de la tuberculosis en las comu-nidades indígenas de Puerto Nariño, Amazonas.Materiales y Métodos Estudio descriptivo transversal en 23 comunidades indígenas, empleando la búsqueda activa de casos mediante consultas médicas casa a casa. Se identificaron y evaluaron individuos sintomáticos respiratorios (sr), definidos como aquellos que tenía tos de cualquier duración. Las evaluaciones diagnósticas incluyeron baciloscopias seriadas de esputo y cultivos en medio líquido mgit™ y medio sólido de Löwenstein-Jensen (lj). Los cultivos identificados como complejo Mycobacterium tuberculosis se sometieron a pruebas de susceptibilidad a medica-mentos antituberculosos de primera línea. Los casos confirmados de tuberculosis se notificaron al sistema de salud. El estudio excluyó del análisis a personas no indígenas y clasificó los casos por edad. Se georreferenciaron las comunida-des indígenas y los casos de tuberculosis.Resultados De la población examinada, el 95% (5 837 individuos) fueron indígenas, el 16,7% (972/5 837) fueron sin-tomáticos respiratorios. Se diagnosticaron 76 casos de tuberculosis, de los cuales el 43,4% fue tuberculosis infantil. Los cultivos de mgit™ fueron positivos en todos los casos de tuberculosis y el 18,2% (6/33) de los niños menores de 15 años tuvieron baciloscopia de esputo positiva. Se identificó un caso de tuberculosis multirresistente (tb-mdr) en un niño. Conclusiones La prevalencia de tuberculosis fue casi 50 veces mayor en la población indígena en comparación con la población general colombiana, según informes oficiales. Los hallazgos resaltan un problema crítico de salud pública, por lo que se necesitan intervenciones específicas para abordar esta problemática.

Título traducido de la contribución	Alta prevalencia de tuberculosis pulmonar en la población indígena de Puerto Nariño, Amazonía de Colombia
Idioma original	Inglés
Páginas (desde-hasta)	1-11
Número de páginas	11
Publicación	Revista de Salud Publica
Volumen	27
N.º	1
DOI	https://doi.org/10.15446/rsap.v27n1.117145
Estado	Publicada - 01 ene. 2025
Publicado de forma externa	Sí

Palabras clave

Tuberculosis
poblaciones indígenas
Puerto Nariño
tuberculosis infantil
epidemiología
sintomáticos respiratorios

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

Acceder al documento

10.15446/rsap.v27n1.117145

Otros archivos y enlaces

Citar esto

@article{c334b45f9b09473faa31b656e9f04051,

title = "High prevalence of pulmonary tuberculosis in the indigenous population of Puerto Nari{\~n}o, Colombian Amazonia",

abstract = "Tuberculosis (TB) remains a significant public health challenge, disproportionately impacting vulnerable groups, particularly indigenous populations. Objetive To investigate the epidemiological behavior of TB among the indigenous communities in Puerto Nari{\~n}o, Amazonas. Materials and Methods Descriptive cross-sectional study across 23 indigenous communities, employing an active case-finding approach through house-to-house medical consultations. Respiratory symptomatic (RS) individuals, defined as those with a cough of any duration, were identified and assessed. Diagnostic evaluations included serial sputum smear microscopy and cultures using MGIT{\texttrademark} liquid and L{\"o}wenstein-Jensen (LJ) solid media. Cultures identified as Mycobacterium tuberculosis complex underwent drug susceptibility testing for first-line anti-TB medications. Confirmed TB cases were reported to the healthcare system. The study excluded non-indigenous individuals from the analysis and categorized cases by age. The indigenous communities and TB cases were geographically mapped. Results Of the population examined, 95\% (5,837 individuals) were indigenous, with 16.7\% (972/5837) identified as RS. Seventy-six TB cases were diagnosed, with childhood TB accounting for 43.4\% of the cases. MGIT{\texttrademark} cultures were positive in all TB cases, and 18.2\% (6/33) of children under 15 had positive sputum smears. Notably, one case of multidrug-resistant TB (MDR-TB) was reported in a child. Conclusions The prevalence of TB was almost 50 times higher in the indigenous, than in the general Colombian population according to official reports. The findings highlight a critical public health concern, with TB prevalence significantly higher among indigenous populations in Puerto Nari{\~n}o compared to the general Colombian population. Targeted interventions are urgently needed to address this disparity.",

keywords = "childhood tuberculosis, epidemiology, indigenous population, Puerto Nari{\~n}o, respiratory symptoms, Tuberculosis, Tuberculosis, poblaciones ind{\'i}genas, Puerto Nari{\~n}o, tuberculosis infantil, epidemiolog{\'i}a, sintom{\'a}ticos respiratorios",

author = "Mape, \{Clara V.\} and Alejandro Vega and Sonia Valencia and Francy P{\'e}rez-Llanos and Carlos Parra-L{\'o}pez and Ricardo S{\'a}nchez and Myriam Navarrete and Murcia, \{Martha I.\}",

year = "2025",

month = jan,

day = "1",

doi = "10.15446/rsap.v27n1.117145",

language = "English",

volume = "27",

pages = "1--11",

journal = "Revista de Salud Publica",

issn = "0124-0064",

publisher = "Universidad Nacional de Colombia",

number = "1",

}

TY - JOUR

T1 - High prevalence of pulmonary tuberculosis in the indigenous population of Puerto Nariño, Colombian Amazonia

AU - Mape, Clara V.

AU - Vega, Alejandro

AU - Valencia, Sonia

AU - Pérez-Llanos, Francy

AU - Parra-López, Carlos

AU - Sánchez, Ricardo

AU - Navarrete, Myriam

AU - Murcia, Martha I.

PY - 2025/1/1

Y1 - 2025/1/1

N2 - Tuberculosis (TB) remains a significant public health challenge, disproportionately impacting vulnerable groups, particularly indigenous populations. Objetive To investigate the epidemiological behavior of TB among the indigenous communities in Puerto Nariño, Amazonas. Materials and Methods Descriptive cross-sectional study across 23 indigenous communities, employing an active case-finding approach through house-to-house medical consultations. Respiratory symptomatic (RS) individuals, defined as those with a cough of any duration, were identified and assessed. Diagnostic evaluations included serial sputum smear microscopy and cultures using MGIT™ liquid and Löwenstein-Jensen (LJ) solid media. Cultures identified as Mycobacterium tuberculosis complex underwent drug susceptibility testing for first-line anti-TB medications. Confirmed TB cases were reported to the healthcare system. The study excluded non-indigenous individuals from the analysis and categorized cases by age. The indigenous communities and TB cases were geographically mapped. Results Of the population examined, 95% (5,837 individuals) were indigenous, with 16.7% (972/5837) identified as RS. Seventy-six TB cases were diagnosed, with childhood TB accounting for 43.4% of the cases. MGIT™ cultures were positive in all TB cases, and 18.2% (6/33) of children under 15 had positive sputum smears. Notably, one case of multidrug-resistant TB (MDR-TB) was reported in a child. Conclusions The prevalence of TB was almost 50 times higher in the indigenous, than in the general Colombian population according to official reports. The findings highlight a critical public health concern, with TB prevalence significantly higher among indigenous populations in Puerto Nariño compared to the general Colombian population. Targeted interventions are urgently needed to address this disparity.

AB - Tuberculosis (TB) remains a significant public health challenge, disproportionately impacting vulnerable groups, particularly indigenous populations. Objetive To investigate the epidemiological behavior of TB among the indigenous communities in Puerto Nariño, Amazonas. Materials and Methods Descriptive cross-sectional study across 23 indigenous communities, employing an active case-finding approach through house-to-house medical consultations. Respiratory symptomatic (RS) individuals, defined as those with a cough of any duration, were identified and assessed. Diagnostic evaluations included serial sputum smear microscopy and cultures using MGIT™ liquid and Löwenstein-Jensen (LJ) solid media. Cultures identified as Mycobacterium tuberculosis complex underwent drug susceptibility testing for first-line anti-TB medications. Confirmed TB cases were reported to the healthcare system. The study excluded non-indigenous individuals from the analysis and categorized cases by age. The indigenous communities and TB cases were geographically mapped. Results Of the population examined, 95% (5,837 individuals) were indigenous, with 16.7% (972/5837) identified as RS. Seventy-six TB cases were diagnosed, with childhood TB accounting for 43.4% of the cases. MGIT™ cultures were positive in all TB cases, and 18.2% (6/33) of children under 15 had positive sputum smears. Notably, one case of multidrug-resistant TB (MDR-TB) was reported in a child. Conclusions The prevalence of TB was almost 50 times higher in the indigenous, than in the general Colombian population according to official reports. The findings highlight a critical public health concern, with TB prevalence significantly higher among indigenous populations in Puerto Nariño compared to the general Colombian population. Targeted interventions are urgently needed to address this disparity.

KW - childhood tuberculosis

KW - epidemiology

KW - indigenous population

KW - Puerto Nariño

KW - respiratory symptoms

KW - Tuberculosis

KW - poblaciones indígenas

KW - Puerto Nariño

KW - tuberculosis infantil

KW - epidemiología

KW - sintomáticos respiratorios

UR - https://www.scopus.com/pages/publications/86000551088

UR - https://revistas.unal.edu.co/index.php/revsaludpublica/article/view/117145/94124

U2 - 10.15446/rsap.v27n1.117145

DO - 10.15446/rsap.v27n1.117145

M3 - Article

AN - SCOPUS:86000551088

SN - 0124-0064

VL - 27

SP - 1

EP - 11

JO - Revista de Salud Publica

JF - Revista de Salud Publica

IS - 1

ER -

High prevalence of pulmonary tuberculosis in the indigenous population of Puerto Nariño, Colombian Amazonia

Resumen

Palabras clave

ODS de las Naciones Unidas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto