TY - JOUR
T1 - Factors associated with in-hospital mortality in octogenarians managed by geriatric service in a referral hospital in Colombia
AU - Cortés-Bahamón, Carlos Mario
AU - Rodriguez Angel, Jenny Paola
AU - Ballesteros Tapias, Jennifer Katherine
AU - Chavarro Carvajal, Diego Andres
AU - Muñoz Velandia, Oscar Mauricio
N1 - Cortes Bahamon CM, Rodríguez Ángel J, Ballesteros Tapias JK, Chavarro-Carvajal DA, Muñoz OM. Factors associated with in-hospital mortality in octogenarians managed by geriatric service in a referral hospital in Colombia. SAGE Open Medicine. 2025;13. doi:10.1177/20503121251317354
PY - 2025/2/7
Y1 - 2025/2/7
N2 - Introduction:The demographic transition has significantly increased the number of hospitalizations in octogenarian patients. Previous studies have documented the importance of clinical, functional, and cognitive variables for in-hospital mortality risk, but their frequency and importance in Latin American populations is yet to be described. It is important because Colombia has multiple ethnic races, with different types of longevity, and we have a history of social violence that affects our life expectancy. The aim of this study is to define which risk factors are associated with in-hospital mortality in octogenarians, and how frequent they are and quantify the weight of each of these factors in the outcomes.Methodology:We present an analytical observational retrospective cohort study in adult patients over 80 years of age hospitalized and followed by the geriatrics service at Hospital Universitario San Ignacio (Bogotá, Colombia). The association between in-hospital mortality and multiple clinical, functional, and cognitive variables was evaluated by means of univariate and multivariate logistic regression analysis.Results:A total of 1235 hospitalizations were analyzed (age 85.5 ± 4.4 years, 58.62% women). Malnutrition was documented in 22.4%, dependency for basic activities (Barthel ⩽ 95) in 75.9%, and positive screening for frailty (FRAIL ⩾ 3) in 55.3%. Mortality was 5.67%. Factors independently associated with mortality were history of cancer (Odds ratio (OR): 2.31; 95% Confidence interval (CI): 1.34–3.98, p < 0.003), delirium (OR: 2.48; 95% CI: 1.44–4.28, p < 0.001), malnutrition (OR: 2.50; 95% CI: 1.46–4.28; p = 0.001), frailty (OR: 2.25; 95% CI: 1.13–4.45, p = 0.019), tachypnea on admission (OR: 1.09; 95% CI: 1.03–1.14, p = 0.002), and creatinine elevation (OR: 2.47; 95% CI: 1.47–4.15, p = 0.001).Conclusion:Factors easily identifiable at hospital admission and amenable to intervention could predict an increased risk of mortality in octogenarian patients, such as the presence of malnutrition, frailty, and delirium. These findings facilitate the estimation of mortality risk and serve as a starting point to investigate the potential benefit of early interventions in this population.
AB - Introduction:The demographic transition has significantly increased the number of hospitalizations in octogenarian patients. Previous studies have documented the importance of clinical, functional, and cognitive variables for in-hospital mortality risk, but their frequency and importance in Latin American populations is yet to be described. It is important because Colombia has multiple ethnic races, with different types of longevity, and we have a history of social violence that affects our life expectancy. The aim of this study is to define which risk factors are associated with in-hospital mortality in octogenarians, and how frequent they are and quantify the weight of each of these factors in the outcomes.Methodology:We present an analytical observational retrospective cohort study in adult patients over 80 years of age hospitalized and followed by the geriatrics service at Hospital Universitario San Ignacio (Bogotá, Colombia). The association between in-hospital mortality and multiple clinical, functional, and cognitive variables was evaluated by means of univariate and multivariate logistic regression analysis.Results:A total of 1235 hospitalizations were analyzed (age 85.5 ± 4.4 years, 58.62% women). Malnutrition was documented in 22.4%, dependency for basic activities (Barthel ⩽ 95) in 75.9%, and positive screening for frailty (FRAIL ⩾ 3) in 55.3%. Mortality was 5.67%. Factors independently associated with mortality were history of cancer (Odds ratio (OR): 2.31; 95% Confidence interval (CI): 1.34–3.98, p < 0.003), delirium (OR: 2.48; 95% CI: 1.44–4.28, p < 0.001), malnutrition (OR: 2.50; 95% CI: 1.46–4.28; p = 0.001), frailty (OR: 2.25; 95% CI: 1.13–4.45, p = 0.019), tachypnea on admission (OR: 1.09; 95% CI: 1.03–1.14, p = 0.002), and creatinine elevation (OR: 2.47; 95% CI: 1.47–4.15, p = 0.001).Conclusion:Factors easily identifiable at hospital admission and amenable to intervention could predict an increased risk of mortality in octogenarian patients, such as the presence of malnutrition, frailty, and delirium. These findings facilitate the estimation of mortality risk and serve as a starting point to investigate the potential benefit of early interventions in this population.
KW - delirium
KW - older adults
KW - frailty
KW - Hospital mortality
KW - malnutrition
KW - delirium
KW - frailty
KW - hospital mortality
KW - malnutrition
KW - older adults
UR - http://www.scopus.com/inward/record.url?scp=85217178448&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/d356feac-b585-32f3-8ba0-b86a5db4b5b7/
UR - https://perfilesycapacidades.javeriana.edu.co/en/publications/1f181a2d-dd4e-4d11-9dbe-a104ab8edf58
U2 - 10.1177/20503121251317354
DO - 10.1177/20503121251317354
M3 - Article
AN - SCOPUS:85217178448
SN - 2050-3121
VL - 13
SP - 1
EP - 7
JO - SAGE Open Medicine
JF - SAGE Open Medicine
ER -