Estudio fitoquímico de hojas de Uncaria guianensis y evaluación de actividad antibacteriana

Juliet Angélica Prieto Rodríguez; Oscar Javier Patiño Ladino; Liliana Lesmes; Jose Manuel Lozano; Luis Enrique Cuca Suárez

doi:10.1590/S0044-59672011000200017

Estudio fitoquímico de hojas de Uncaria guianensis y evaluación de actividad antibacteriana

Juliet Angélica Prieto Rodríguez, Oscar Javier Patiño Ladino, Liliana Lesmes, Jose Manuel Lozano, Luis Enrique Cuca Suárez

Producción: Contribución a una revista › Artículo › revisión exhaustiva

10 Citas (Scopus)

Resumen

A chlorin compound, pheophorbide a ethyl ester and a mixture of sterols known as β sitosterol and stigmasterol, were isolated from the petroleum ether extract of Uncaria guianensis (Rubiaceae) leaves. Their structures were elucidated by detailed analysis of NMR spectra, including bidimensional techniques and by comparison with literature data. The antibacterial activity for the pheophorbide a ethyl ester was evaluated against two Gram (+) strains: S. aureus ATCC 6538 y E. faecalis ATCC 29212 and three Gram (-) strains: E. coli ATCC 25922, S. typhimurium ATCC 14028s y S. typhimurium MS7953S. aureus ATCC 6538 and E. fecalis ATCC 29212, finding significant activity against S. aureus 6538, E. faecalis 29212, S. tiphymurium MS7953 and E. coli 25922.

Título traducido de la contribución	Phytochemical study of Uncaria guianensis leaves and antibacterial activity evaluation
Idioma original	Portugués
Páginas (desde-hasta)	303-310
Número de páginas	8
Publicación	Acta Amazonica
Volumen	41
N.º	2
DOI	https://doi.org/10.1590/S0044-59672011000200017
Estado	Publicada - 2011
Publicado de forma externa	Sí

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title = "Estudio fitoqu{\'i}mico de hojas de Uncaria guianensis y evaluaci{\'o}n de actividad antibacteriana",

abstract = "A chlorin compound, pheophorbide a ethyl ester and a mixture of sterols known as β sitosterol and stigmasterol, were isolated from the petroleum ether extract of Uncaria guianensis (Rubiaceae) leaves. Their structures were elucidated by detailed analysis of NMR spectra, including bidimensional techniques and by comparison with literature data. The antibacterial activity for the pheophorbide a ethyl ester was evaluated against two Gram (+) strains: S. aureus ATCC 6538 y E. faecalis ATCC 29212 and three Gram (-) strains: E. coli ATCC 25922, S. typhimurium ATCC 14028s y S. typhimurium MS7953S. aureus ATCC 6538 and E. fecalis ATCC 29212, finding significant activity against S. aureus 6538, E. faecalis 29212, S. tiphymurium MS7953 and E. coli 25922.",

keywords = "Antimicrobial activity, Chlorin, Pheophorbide a ethyl ester, Rubiaceae, Uncaria guianensis",

author = "{Prieto Rodr{\'i}guez}, {Juliet Ang{\'e}lica} and {Pati{\~n}o Ladino}, {Oscar Javier} and Liliana Lesmes and Lozano, {Jose Manuel} and {Cuca Su{\'a}rez}, {Luis Enrique}",

year = "2011",

doi = "10.1590/S0044-59672011000200017",

language = "Portugu{\'e}s",

volume = "41",

pages = "303--310",

journal = "Acta Amazonica",

issn = "0044-5967",

publisher = "Instituto Nacional de Pesquisas da Amazonia",

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T1 - Estudio fitoquímico de hojas de Uncaria guianensis y evaluación de actividad antibacteriana

AU - Prieto Rodríguez, Juliet Angélica

AU - Patiño Ladino, Oscar Javier

AU - Lesmes, Liliana

AU - Lozano, Jose Manuel

AU - Cuca Suárez, Luis Enrique

PY - 2011

Y1 - 2011

N2 - A chlorin compound, pheophorbide a ethyl ester and a mixture of sterols known as β sitosterol and stigmasterol, were isolated from the petroleum ether extract of Uncaria guianensis (Rubiaceae) leaves. Their structures were elucidated by detailed analysis of NMR spectra, including bidimensional techniques and by comparison with literature data. The antibacterial activity for the pheophorbide a ethyl ester was evaluated against two Gram (+) strains: S. aureus ATCC 6538 y E. faecalis ATCC 29212 and three Gram (-) strains: E. coli ATCC 25922, S. typhimurium ATCC 14028s y S. typhimurium MS7953S. aureus ATCC 6538 and E. fecalis ATCC 29212, finding significant activity against S. aureus 6538, E. faecalis 29212, S. tiphymurium MS7953 and E. coli 25922.

AB - A chlorin compound, pheophorbide a ethyl ester and a mixture of sterols known as β sitosterol and stigmasterol, were isolated from the petroleum ether extract of Uncaria guianensis (Rubiaceae) leaves. Their structures were elucidated by detailed analysis of NMR spectra, including bidimensional techniques and by comparison with literature data. The antibacterial activity for the pheophorbide a ethyl ester was evaluated against two Gram (+) strains: S. aureus ATCC 6538 y E. faecalis ATCC 29212 and three Gram (-) strains: E. coli ATCC 25922, S. typhimurium ATCC 14028s y S. typhimurium MS7953S. aureus ATCC 6538 and E. fecalis ATCC 29212, finding significant activity against S. aureus 6538, E. faecalis 29212, S. tiphymurium MS7953 and E. coli 25922.

KW - Antimicrobial activity

KW - Chlorin

KW - Pheophorbide a ethyl ester

KW - Rubiaceae

KW - Uncaria guianensis

UR - http://www.scopus.com/inward/record.url?scp=79956355335&partnerID=8YFLogxK

U2 - 10.1590/S0044-59672011000200017

DO - 10.1590/S0044-59672011000200017

M3 - Artículo

AN - SCOPUS:79956355335

SN - 0044-5967

VL - 41

SP - 303

EP - 310

JO - Acta Amazonica

JF - Acta Amazonica

IS - 2

ER -

Estudio fitoquímico de hojas de Uncaria guianensis y evaluación de actividad antibacteriana

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