TY - JOUR
T1 - E6 molecular variants of human papillomavirus (HPV) type 16
T2 - An updated and unified criterion for clustering and nomenclature
AU - Huertas-Salgado, Antonio
AU - Martín-Gámez, Diana C.
AU - Moreno, Pablo
AU - Murillo, Raúl
AU - Bravo, María Mercedes
AU - Villa, Luisa
AU - Molano, Mónica
N1 - Funding Information:
This work was supported by Colciencias : Grant 2101-04-14375 , and DNP Grants 41030310-5 and 41030310-10 .
PY - 2011/2/5
Y1 - 2011/2/5
N2 - Reports on taxonomic identification of E6/HPV 16 variants, don't have a worldwide, updated and unified criterion for clustering and nomenclature. Our aim was to update the existing criterion and propose a new one for clustering and nomenclature for E6/HPV 16 molecular variants based on the descriptive and comparative analyses of nucleotide sequences. A systematic search of the publications between 1991 and 2010 was carried out in PUBMED and manually. 240 E6/HPV 16 variants were identified. 157 were classified as European (E), 24 as Asian (As), 14 as Asian American (AA), 11 as North American 1 (NA 1), 19 as African 1 (Af 1) and 15 as African 2 (Af 2). Three classes were determined for the E, 3 each for the As, Af 2 and AA branches, 4 classes for the NA 1 and 6 for the Af 1 branch. This study reports our results and proposes an updated criterion for clustering and nomenclature that will be useful for E6 variant identification.
AB - Reports on taxonomic identification of E6/HPV 16 variants, don't have a worldwide, updated and unified criterion for clustering and nomenclature. Our aim was to update the existing criterion and propose a new one for clustering and nomenclature for E6/HPV 16 molecular variants based on the descriptive and comparative analyses of nucleotide sequences. A systematic search of the publications between 1991 and 2010 was carried out in PUBMED and manually. 240 E6/HPV 16 variants were identified. 157 were classified as European (E), 24 as Asian (As), 14 as Asian American (AA), 11 as North American 1 (NA 1), 19 as African 1 (Af 1) and 15 as African 2 (Af 2). Three classes were determined for the E, 3 each for the As, Af 2 and AA branches, 4 classes for the NA 1 and 6 for the Af 1 branch. This study reports our results and proposes an updated criterion for clustering and nomenclature that will be useful for E6 variant identification.
KW - E6
KW - HPV 16
KW - Molecular variants
KW - Taxonomic determination
UR - http://www.scopus.com/inward/record.url?scp=78650730325&partnerID=8YFLogxK
U2 - 10.1016/j.virol.2010.10.039
DO - 10.1016/j.virol.2010.10.039
M3 - Article
AN - SCOPUS:78650730325
SN - 0042-6822
VL - 410
SP - 201
EP - 215
JO - Virology
JF - Virology
IS - 1
ER -