Delirium in Elderly Hospitalized Patients: Analyzing Clinical and Social Determinants in a ColombianRetrospective Cohort

Alejandra Ospina Lehman; Maria Camila Castañeda Gómez; Eduardo Jose Pabon Martinez; Juan Pablo Vigoya Aponte; Santiago  Orozco Castro; Diego Andres Chavarro Carvajal; Carlos Alberto  Cano-Gutiérrez

doi:10.1002/gps.70079

Delirium in Elderly Hospitalized Patients: Analyzing Clinical and Social Determinants in a ColombianRetrospective Cohort

Título traducido de la contribución: Delirium en pacientes adultos mayores hospitalizados: analizando determinantes sociales y clínicos en una cohorte retrospectiva colombiana

Alejandra Ospina Lehman, Maria Camila Castañeda Gómez, Eduardo Jose Pabon Martinez, Juan Pablo Vigoya Aponte, Santiago Orozco Castro, Diego Andres Chavarro Carvajal, Carlos Alberto Cano-Gutiérrez

Universidad Javeriana

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Resumen

Objetivo: Este estudio busca describir los determinantes clínicos y sociales asociados con el delirio en pacientes adultos mayores hospitalizados en el Servicio de Geriatría del Hospital Universitario San Ignacio (HUSI), en Bogotá, Colombia, entre junio de 2019 y junio de 2022. Métodos: Se realizó un estudio analítico retrospectivo. Los datos se extrajeron de la historia clínica electrónica del hospital. El desenlace principal fue el riesgo de delirio al ingreso. Las variables de exposición incluyeron factores clínicos (p. ej., desnutrición, demencia, disfagia orofaríngea) y sociales (p. ej., vivir solo, redes sociales). Se evaluaron las asociaciones entre el delirio y las variables de exposición mediante un modelo de regresión logística multivariante. Resultados: La cohorte estudiada estuvo compuesta por 4601 pacientes, con una edad media de 83,93 años y un 56,26 % de mujeres. La prevalencia de delirio al ingreso fue del 22,39 %. Los factores clave asociados con el delirio incluyeron edad avanzada (OR 1,04, IC 95% 1,01-1,06), desnutrición (OR 2,42, IC 95% 1,93-2,79), demencia (OR 2,57, IC 95% 2,02-3,38), deterioro funcional (OR 2,50, IC 95% 1,74-3,59) y disfagia orofaríngea (OR 1,49, IC 95% 1,08-1,99). Los determinantes sociales como el sexo femenino, las redes sociales limitadas, vivir solo y la afiliación al régimen de salud subsidiado no se asociaron significativamente con el delirio. Conclusión: El delirio al ingreso es altamente prevalente entre los pacientes ancianos hospitalizados y se asocia con factores clínicos, particularmente desnutrición, demencia y disfagia orofaríngea. Aunque no se encontraron asociaciones significativas entre los determinantes sociales de la salud (DSS) y el delirio en esta cohorte, se necesita más investigación en diversos entornos de atención médica para comprender mejor el impacto más amplio de los DSS en el riesgo de delirio.

Título traducido de la contribución	Delirium en pacientes adultos mayores hospitalizados: analizando determinantes sociales y clínicos en una cohorte retrospectiva colombiana
Idioma original	Inglés
Páginas (desde-hasta)	1-7
Número de páginas	7
Publicación	International Journal of Geriatric Psychiatry
Volumen	40
DOI	https://doi.org/10.1002/gps.70079
Estado	Publicada - 21 abr. 2025
Evento	XVIII Congreso de la Asociación Colombiana de Gerontología y Geriatría - Neomundo, Bucaramanga, Colombia Duración: 23 may. 2024 → 25 may. 2024 https://acgg.org.co/congreso2024/

Palabras clave

Delirium
prevalence
aged

ODS de las Naciones Unidas

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Ospina Lehman, A., Castañeda Gómez, M. C., Pabon Martinez, E. J., Vigoya Aponte, J. P., Orozco Castro, S., Chavarro Carvajal, D. A., & Cano-Gutiérrez, C. A. (2025). Delirium in Elderly Hospitalized Patients: Analyzing Clinical and Social Determinants in a ColombianRetrospective Cohort. International Journal of Geriatric Psychiatry, 40, 1-7. https://doi.org/10.1002/gps.70079

@article{0354ea32d6d042508c105861e74a6ebe,

title = "Delirium in Elderly Hospitalized Patients: Analyzing Clinical and Social Determinants in a ColombianRetrospective Cohort",

abstract = "ObjectiveThis study aims to describe the clinical and social determinants associated with delirium in elderly patients hospitalized in the geriatrics department of Hospital Universitario San Ignacio (HUSI), in Bogot{\'a}, Colombia, between June 2019 and June 2022.MethodsWe conducted a retrospective analytical study. Data were extracted from the hospital's electronic medical records. The primary outcome was delirium upon admission. Exposure variables included clinical (e.g., malnutrition, dementia, oropharyngeal dysphagia) and social factors (e.g., living alone, social networks). Associations between delirium and exposure variables were assessed using a multivariate logistic regression model.ResultsThe studied cohort comprised 4601 patients, mean age of 83.93 years and 56.26% were women. The prevalence of delirium upon admission was 22.39%. Key factors associated with delirium included older age (OR 1.04, 95% CI 1.01–1.06), malnutrition (OR 2.42, 95% CI 1.93–2.79), dementia (OR 2.57, 95% CI 2.02–3.38), functional impairment (OR 2.50, 95% CI 1.74–3.59), and oropharyngeal dysphagia (OR 1.49, 95% CI 1.08–1.99). Social determinants such as female sex, limited social networks, living alone, and enrollment in the subsidized health regime were not significantly associated with delirium.ConclusionDelirium upon admission is highly prevalent among elderly inpatients and is associated with clinical factors, particularly malnutrition, dementia, and oropharyngeal dysphagia. Although no significant associations were found between social determinants of health (SDH) and delirium in this cohort, further research in diverse healthcare settings is needed to better understand the broader impact of SDH on delirium risk.",

keywords = "Delirium, prevalence, aged",

author = "{Ospina Lehman}, Alejandra and {Casta{\~n}eda G{\'o}mez}, {Maria Camila} and {Pabon Martinez}, {Eduardo Jose} and {Vigoya Aponte}, {Juan Pablo} and {Orozco Castro}, Santiago and {Chavarro Carvajal}, {Diego Andres} and Cano-Guti{\'e}rrez, {Carlos Alberto}",

year = "2025",

month = apr,

day = "21",

doi = "10.1002/gps.70079",

language = "English",

volume = "40",

pages = "1--7",

journal = "International Journal of Geriatric Psychiatry",

issn = "0885-6230",

publisher = "John Wiley and Sons Ltd",

note = "XVIII Congreso de la Asociaci{\'o}n Colombiana de Gerontolog{\'i}a y Geriatr{\'i}a ; Conference date: 23-05-2024 Through 25-05-2024",

url = "https://acgg.org.co/congreso2024/",

}

Ospina Lehman, A, Castañeda Gómez, MC, Pabon Martinez, EJ, Vigoya Aponte, JP, Orozco Castro, S, Chavarro Carvajal, DA & Cano-Gutiérrez, CA 2025, 'Delirium in Elderly Hospitalized Patients: Analyzing Clinical and Social Determinants in a ColombianRetrospective Cohort', International Journal of Geriatric Psychiatry, vol. 40, pp. 1-7. https://doi.org/10.1002/gps.70079

Delirium in Elderly Hospitalized Patients: Analyzing Clinical and Social Determinants in a ColombianRetrospective Cohort. / Ospina Lehman, Alejandra; Castañeda Gómez, Maria Camila; Pabon Martinez, Eduardo Jose et al.
En: International Journal of Geriatric Psychiatry, Vol. 40, 21.04.2025, p. 1-7.

Producción: Contribución a una revista › Artículo › revisión exhaustiva

TY - JOUR

T1 - Delirium in Elderly Hospitalized Patients: Analyzing Clinical and Social Determinants in a ColombianRetrospective Cohort

AU - Ospina Lehman, Alejandra

AU - Castañeda Gómez, Maria Camila

AU - Pabon Martinez, Eduardo Jose

AU - Vigoya Aponte, Juan Pablo

AU - Orozco Castro, Santiago

AU - Chavarro Carvajal, Diego Andres

AU - Cano-Gutiérrez, Carlos Alberto

PY - 2025/4/21

Y1 - 2025/4/21

N2 - ObjectiveThis study aims to describe the clinical and social determinants associated with delirium in elderly patients hospitalized in the geriatrics department of Hospital Universitario San Ignacio (HUSI), in Bogotá, Colombia, between June 2019 and June 2022.MethodsWe conducted a retrospective analytical study. Data were extracted from the hospital's electronic medical records. The primary outcome was delirium upon admission. Exposure variables included clinical (e.g., malnutrition, dementia, oropharyngeal dysphagia) and social factors (e.g., living alone, social networks). Associations between delirium and exposure variables were assessed using a multivariate logistic regression model.ResultsThe studied cohort comprised 4601 patients, mean age of 83.93 years and 56.26% were women. The prevalence of delirium upon admission was 22.39%. Key factors associated with delirium included older age (OR 1.04, 95% CI 1.01–1.06), malnutrition (OR 2.42, 95% CI 1.93–2.79), dementia (OR 2.57, 95% CI 2.02–3.38), functional impairment (OR 2.50, 95% CI 1.74–3.59), and oropharyngeal dysphagia (OR 1.49, 95% CI 1.08–1.99). Social determinants such as female sex, limited social networks, living alone, and enrollment in the subsidized health regime were not significantly associated with delirium.ConclusionDelirium upon admission is highly prevalent among elderly inpatients and is associated with clinical factors, particularly malnutrition, dementia, and oropharyngeal dysphagia. Although no significant associations were found between social determinants of health (SDH) and delirium in this cohort, further research in diverse healthcare settings is needed to better understand the broader impact of SDH on delirium risk.

AB - ObjectiveThis study aims to describe the clinical and social determinants associated with delirium in elderly patients hospitalized in the geriatrics department of Hospital Universitario San Ignacio (HUSI), in Bogotá, Colombia, between June 2019 and June 2022.MethodsWe conducted a retrospective analytical study. Data were extracted from the hospital's electronic medical records. The primary outcome was delirium upon admission. Exposure variables included clinical (e.g., malnutrition, dementia, oropharyngeal dysphagia) and social factors (e.g., living alone, social networks). Associations between delirium and exposure variables were assessed using a multivariate logistic regression model.ResultsThe studied cohort comprised 4601 patients, mean age of 83.93 years and 56.26% were women. The prevalence of delirium upon admission was 22.39%. Key factors associated with delirium included older age (OR 1.04, 95% CI 1.01–1.06), malnutrition (OR 2.42, 95% CI 1.93–2.79), dementia (OR 2.57, 95% CI 2.02–3.38), functional impairment (OR 2.50, 95% CI 1.74–3.59), and oropharyngeal dysphagia (OR 1.49, 95% CI 1.08–1.99). Social determinants such as female sex, limited social networks, living alone, and enrollment in the subsidized health regime were not significantly associated with delirium.ConclusionDelirium upon admission is highly prevalent among elderly inpatients and is associated with clinical factors, particularly malnutrition, dementia, and oropharyngeal dysphagia. Although no significant associations were found between social determinants of health (SDH) and delirium in this cohort, further research in diverse healthcare settings is needed to better understand the broader impact of SDH on delirium risk.

KW - Delirium

KW - prevalence

KW - aged

U2 - 10.1002/gps.70079

DO - 10.1002/gps.70079

M3 - Article

SN - 0885-6230

VL - 40

SP - 1

EP - 7

JO - International Journal of Geriatric Psychiatry

JF - International Journal of Geriatric Psychiatry

T2 - XVIII Congreso de la Asociación Colombiana de Gerontología y Geriatría

Y2 - 23 May 2024 through 25 May 2024

ER -

Delirium in Elderly Hospitalized Patients: Analyzing Clinical and Social Determinants in a ColombianRetrospective Cohort

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