CLINICAL, DIAGNOSTIC AND THERAPEUTIC CHARACTERIZATION OF PATIENTS WITH PANCREATIC COLLECTIONS DUE TO ACUTE PANCREATITIS IN A REFERRAL HOSPITAL

Background – Pancreatic collections are a common complication
of acute pancreatitis. In Latin America, information on the types of
pancreatic collections and their management is limited and may vary
between regions depending on the availability of highly specialised and
minimally invasive treatment resources. Methods – Retrospective cohort
of patients with acute pancreatic collections secondary to acute pancreatitis
treated at the Hospital Universitario San Ignacio, Bogotá (Colombia)
between 2012–2023. Clinical characteristics, laboratory profiles and treatment
received were described, comparing those who had a fatal outcome
with those who did not. Results – Of 689 patients with acute pancreatitis,
113 presented with pancreatic collection (55.1% women, mean age 55
years). Of these, 47.8% presented with acute necrotic collection, 36.3%
with acute fluid collection, 9.7% with walled-off necrosis and 6.2% with
pancreatic pseudocyst. C-reactive protein, BUN, creatinine levels (at admission
and at 48 hours), PaO2/FiO2 (at admission and at 48 hours) and
antibiotic use were significantly associated with mortality (P<0.05). The
majority of acute necrotic collections, walled-off necrosis and pseudocysts
received interventional management, with minimally invasive and
combined management being more common than surgical management.
Antibiotic management was used in 48.6% of collections, although microbiological
isolation was performed in only 24.7% of cases. Conclusion –
Acute collections are a common and heterogeneous complication of pancreatitis,
requiring intervention more often in complicated collections.
Certain laboratory parameters seem to be more associated with mortality