TY - JOUR
T1 - Cellular location of KMP-11 protein in Trypanosoma rangeli
AU - Diez, Hugo
AU - Sarmiento, Ladys
AU - Caldas, María Leonor
AU - Montilla, Marleny
AU - Thomas, María Del Carmen
AU - Lopez, Manuel Carlos
AU - Puerta, Concepción
PY - 2008/2/1
Y1 - 2008/2/1
N2 - We describe the localization of the KMP-11 protein in the Trypanosoma rangeli parasite determined by immunoelectron microscopy using a monoclonal antibody generated against the Trypanosoma cruzi KMP-11 protein. The data reported herein show that the T. rangeli KMP-11 protein is mainly accumulated in the parasite cytoplasm, the coat, the flagellum, and the flagellar pocket. The high degree of sequence homology between the KMP-11 proteins from both parasites suggests that the KMP-11 protein from T. rangeli, like that of T. cruzi, could also be associated with the parasite cytoskeleton.
AB - We describe the localization of the KMP-11 protein in the Trypanosoma rangeli parasite determined by immunoelectron microscopy using a monoclonal antibody generated against the Trypanosoma cruzi KMP-11 protein. The data reported herein show that the T. rangeli KMP-11 protein is mainly accumulated in the parasite cytoplasm, the coat, the flagellum, and the flagellar pocket. The high degree of sequence homology between the KMP-11 proteins from both parasites suggests that the KMP-11 protein from T. rangeli, like that of T. cruzi, could also be associated with the parasite cytoskeleton.
KW - Immunoelectron microscopy
KW - KMP-11 protein
KW - Kinetoplastid parasites
KW - Trypanosoma cruzi
KW - Trypanosoma rangeli
UR - http://www.scopus.com/inward/record.url?scp=39449130442&partnerID=8YFLogxK
U2 - 10.1089/vbz.2006.0650
DO - 10.1089/vbz.2006.0650
M3 - Article
C2 - 18171105
AN - SCOPUS:39449130442
SN - 1530-3667
VL - 8
SP - 93
EP - 96
JO - Vector-Borne and Zoonotic Diseases
JF - Vector-Borne and Zoonotic Diseases
IS - 1
ER -
