CD8+ T cell response to trypanosoma cruzi antigens during chronic chagas disease

Paola Lasso; Jose Mateus; John Mario González; Adriana Cuéllar; Concepción Puerta

doi:10.1007/978-1-4939-9148-8_26

CD8⁺ T cell response to trypanosoma cruzi antigens during chronic chagas disease

Paola Lasso, Jose Mateus, John Mario González, Adriana Cuéllar, Concepción Puerta

Departamento de Microbiología

Producción: Capítulo del libro/informe/acta de congreso › Capítulo en libro de investigación › revisión exhaustiva

3 Citas (Scopus)

Resumen

Flow cytometry is a valuable technique in cellular immunology that allows evaluating effective parameters of the immune response associated with CD8⁺ T cells. During Chagas disease, infection caused by Trypanosoma cruzi parasite, similar to other intracellular infectious agents, antigen-specific CD8⁺ T cells are essential for controlling the infection. However, CD8⁺ T cell response is only partially effective in some chronic Chagas disease patients. Thus, characterization and phenotyping of T. cruzi-specific CD8⁺ T cells are of great importance during chronic Chagas disease.

Idioma original	Inglés
Título de la publicación alojada	Methods in Molecular Biology
Editorial	Humana Press Inc.
Páginas	349-361
Número de páginas	13
DOI	https://doi.org/10.1007/978-1-4939-9148-8_26
Estado	Publicada - 2019

Serie de la publicación

Nombre	Methods in Molecular Biology
Volumen	1955
ISSN (versión impresa)	1064-3745
ISSN (versión digital)	1940-6029

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abstract = "Flow cytometry is a valuable technique in cellular immunology that allows evaluating effective parameters of the immune response associated with CD8+ T cells. During Chagas disease, infection caused by Trypanosoma cruzi parasite, similar to other intracellular infectious agents, antigen-specific CD8+ T cells are essential for controlling the infection. However, CD8+ T cell response is only partially effective in some chronic Chagas disease patients. Thus, characterization and phenotyping of T. cruzi-specific CD8+ T cells are of great importance during chronic Chagas disease.",

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CD8⁺ T cell response to trypanosoma cruzi antigens during chronic chagas disease. / Lasso, Paola; Mateus, Jose; González, John Mario et al.
Methods in Molecular Biology. Humana Press Inc., 2019. p. 349-361 (Methods in Molecular Biology; Vol. 1955).

Producción: Capítulo del libro/informe/acta de congreso › Capítulo en libro de investigación › revisión exhaustiva

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