TY - JOUR
T1 - Cardiovascular risk and lipid control in older adults
T2 - Compliance with LDL, non-HDL cholesterol, and triglyceride goals in a national cross-sectional study
AU - Bueno, Cristian Orlando Porras
AU - España, Jesús Andres Beltrán
AU - Guzmán, Carolina Murgueitio
AU - Diaz-Brochero, Cándida
AU - Peña, Ángel Alberto García
N1 - Publisher Copyright:
© 2025
PY - 2025/5
Y1 - 2025/5
N2 - Background: Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide. Low-density lipoprotein cholesterol (LDL-C) is a key therapeutic target, yet data on compliance with lipid goals in older adults from low- and middle-income countries are limited. Objective: To evaluate the compliance with lipid profile goals in older adults. Methods: This cross-sectional study analyzed 1270 adults aged ≥60 years from the Survey on Health, Well-being, and Ageing in Latin America and the Caribbean (SABE) Colombia 2015 survey. Cardiovascular risk was assessed via Framingham, ASCVD 2013, and SCORE2 models calibrated for Colombia, and lipid profile compliance was evaluated. Results: Most participants were at high or very high risk according to the SCORE2 (54.10%), ASCVD (10%), and Framingham (10.87%) criteria. LDL-C target compliance was low, ranging from 0.72% (Framingham) to 3.93% (ASCVD). Triglyceride targets were better achieved, with 54.88% meeting goals in the highest SCORE2 category. Conclusions: Older Colombian adults have poor compliance with lipid goals, underscoring the urgent need for enhanced preventive strategies in this population.
AB - Background: Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide. Low-density lipoprotein cholesterol (LDL-C) is a key therapeutic target, yet data on compliance with lipid goals in older adults from low- and middle-income countries are limited. Objective: To evaluate the compliance with lipid profile goals in older adults. Methods: This cross-sectional study analyzed 1270 adults aged ≥60 years from the Survey on Health, Well-being, and Ageing in Latin America and the Caribbean (SABE) Colombia 2015 survey. Cardiovascular risk was assessed via Framingham, ASCVD 2013, and SCORE2 models calibrated for Colombia, and lipid profile compliance was evaluated. Results: Most participants were at high or very high risk according to the SCORE2 (54.10%), ASCVD (10%), and Framingham (10.87%) criteria. LDL-C target compliance was low, ranging from 0.72% (Framingham) to 3.93% (ASCVD). Triglyceride targets were better achieved, with 54.88% meeting goals in the highest SCORE2 category. Conclusions: Older Colombian adults have poor compliance with lipid goals, underscoring the urgent need for enhanced preventive strategies in this population.
KW - Cholesterol
KW - Cross-sectional studies
KW - Heart disease risk factors
KW - LDL
KW - Primary health care
KW - Risk assessment
KW - Triglycerides
UR - http://www.scopus.com/inward/record.url?scp=105005938824&partnerID=8YFLogxK
UR - https://www.lipidjournal.com/action/showPdf?pii=S1933-2874%2825%2900280-6
U2 - 10.1016/j.jacl.2025.04.197
DO - 10.1016/j.jacl.2025.04.197
M3 - Article
SN - 1933-2874
SP - 1
EP - 9
JO - Journal of Clinical Lipidology
JF - Journal of Clinical Lipidology
ER -