TY - JOUR
T1 - Association between cigarette smoking and the prevalence of post-endodontic periapical pathology
T2 - a systematic review and meta-analysis
AU - Caviedes Buchelli, Javier Fernando
AU - Ríos-Osorio, Nestor
AU - Jiménez-Castellanos, Fabio Andrés
AU - Quijano Guauque, Sara Beatriz
AU - Jimenez-Peña, Oscar
AU - García-Perdomo, Herney Andrés
AU - Caviedes-Bucheli, Javier
PY - 2022/6/13
Y1 - 2022/6/13
N2 - Objectives
This systematic review and meta-analysis aimed to assess the association of cigarette smoking with the prevalence of post-endodontic apical periodontitis in humans.
Materials and Methods
We searched through PubMed/Medline, Web of Science, and Scopus from inception to December 2020. Risk of bias was performed by using the Newcastle-Ottawa Scale for cross-sectional, cohort, and case-control studies. We performed the statistical analysis in Review Manager 5.3 (RevMan 5.3).
Results
6 studies met the inclusion criteria for qualitative and quantitative synthesis. Statistical analysis of these studies suggests that there were no differences in the prevalence of post endodontic apical periodontitis (AP) when comparing non-smokers vs smoker subjects regarding patients (odds ratio [OR], 0.68; 95% confidence interval [CI], 0.31–1.49; I2 = 58%) and teeth (OR, 1.71; 95% CI, 0.99–2.93; I2 = 72%).
Conclusions
Our findings suggest that there was no association between cigarette smoking and post-endodontic apical periodontitis, as we did not find statistical differences in the prevalence of post-endodontic AP when comparing non-smokers vs smoker subjects. Therefore, smoking should not be considered a risk factor associated with endodontic failure.
AB - Objectives
This systematic review and meta-analysis aimed to assess the association of cigarette smoking with the prevalence of post-endodontic apical periodontitis in humans.
Materials and Methods
We searched through PubMed/Medline, Web of Science, and Scopus from inception to December 2020. Risk of bias was performed by using the Newcastle-Ottawa Scale for cross-sectional, cohort, and case-control studies. We performed the statistical analysis in Review Manager 5.3 (RevMan 5.3).
Results
6 studies met the inclusion criteria for qualitative and quantitative synthesis. Statistical analysis of these studies suggests that there were no differences in the prevalence of post endodontic apical periodontitis (AP) when comparing non-smokers vs smoker subjects regarding patients (odds ratio [OR], 0.68; 95% confidence interval [CI], 0.31–1.49; I2 = 58%) and teeth (OR, 1.71; 95% CI, 0.99–2.93; I2 = 72%).
Conclusions
Our findings suggest that there was no association between cigarette smoking and post-endodontic apical periodontitis, as we did not find statistical differences in the prevalence of post-endodontic AP when comparing non-smokers vs smoker subjects. Therefore, smoking should not be considered a risk factor associated with endodontic failure.
KW - Root canal treatment
KW - Apical periodontitis
KW - Cigarette smoking
KW - Systematic review
KW - Root canal treatment
KW - Apical periodontitis
KW - Cigarette smoking
KW - Systematic review
U2 - 10.5395/rde.2022.47.e27
DO - 10.5395/rde.2022.47.e27
M3 - Article
SN - 2234-7658
VL - 47
SP - 1
EP - 14
JO - Restorative Dentistry and Endodontics
JF - Restorative Dentistry and Endodontics
IS - 3
ER -