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INIS
enzymes
100%
diseases
66%
therapy
56%
production
55%
sulfates
53%
humans
48%
proteins
37%
storage
29%
mutations
27%
genes
27%
patients
26%
accumulation
25%
bones
23%
in vitro
23%
gene therapy
22%
vectors
20%
evaluation
20%
metabolism
19%
fibroblasts
19%
yeasts
18%
substrates
15%
design
14%
ph value
14%
strains
13%
tools
13%
biology
13%
reduction
12%
stability
12%
reviews
11%
levels
11%
stem cells
11%
concentration
11%
mice
11%
bacteria
11%
modeling
11%
growth
11%
lysosomes
10%
colombia
10%
central nervous system
10%
enzyme activity
10%
chondroitin
10%
transport
10%
microorganisms
10%
errors
10%
amino acids
9%
delivery
9%
escherichia coli
9%
comparative evaluations
9%
lipids
9%
drugs
9%
lactobacillus
9%
interactions
8%
applications
8%
cartilage
8%
peptides
8%
viruses
8%
brain
7%
nanoparticles
7%
promoters
7%
food
6%
oxidation
6%
antibodies
6%
assessments
6%
bioreactors
6%
fungi
6%
oxygen
6%
tissues
6%
values
5%
molecules
5%
gangliosides
5%
glycoproteins
5%
oryza
5%
host
5%
information
5%
genetics
5%
bovine
5%
magnetite
5%
patents
5%
aspergillus
5%
control
5%
in vivo
5%
cavities
5%
Keyphrases
MPS IVA
52%
Recombinant
46%
GALNS
43%
Enzyme Replacement Therapy
34%
N-acetylgalactosamine-6-sulfate Sulfatase
30%
Photosystem II
30%
Lysosomal Storage Disease
27%
Pichia Pastoris
25%
Glycosaminoglycans
21%
Gene Therapy
19%
Fibroblasts
17%
Genome Editing
16%
Keratan Sulfate
13%
Morquio A
13%
Komagataella Phaffii
12%
Morquio Syndrome
12%
Fructooligosaccharides
11%
Pharmacological Chaperone
11%
Colombia
11%
Lysosomal Enzymes
10%
Enzyme Activity
10%
β-hexosaminidase
10%
NCas9
10%
CRISPR Activation
10%
Fructosyltransferase
10%
Lysosome
9%
Bone-targeting
9%
Inborn Errors of Metabolism
9%
Iduronate-2-sulfatase
9%
Computational Analysis
9%
In Vitro Model
9%
Morquio A Disease
9%
Chondroitin-6-sulfate
9%
Laccase
8%
Current Therapies
8%
GM2 Gangliosidosis
8%
Recombinant Enzyme
8%
Recombinant Human
8%
Hematopoietic Stem Cell Transplantation
8%
Cartilage
7%
Escherichia Coli
7%
Methylotrophic Yeast
7%
Central Nervous System
7%
Bacteriocin
7%
Tay-Sachs Disease
6%
Sulfatase Modifying Factor 1 (SUMF1)
6%
Bioreactor
6%
Laccase Activity
6%
Lactobacillus Plantarum
6%
Therapeutic Potential
6%
Antimicrobial Activity
6%
In Vitro Evaluation
6%
Gene Editing
5%
Culture Conditions
5%
Microorganisms
5%
HEK293 Cells
5%
Skeletal Dysplasia
5%
Lysosomal Disease
5%
Escherichia Coli BL21
5%
Bone Lesions
5%
Hydroxyapatite
5%
Non-viral Vectors
5%
PH Stability
5%
Crude Extract
5%
Mucopolysaccharidosis Type IIIB
5%
Computational Approach
5%
In Silico Analysis
5%
Systems Biology
5%
Glycoprotein B
5%
Metabolic Consequences
5%
Biology Study
5%
Ensiling
5%
Aspergillus Oryzae
5%
Trametes Pubescens
5%
Adenovirus
5%
Iron Oxide
5%
Arylsulfatase
5%
Effective Treatment
5%
GM2 Ganglioside
5%
Culture Media
5%
Bone Development
5%
Nanoparticles
5%
Biochemistry, Genetics and Molecular Biology
Enzyme
52%
Mucopolysaccharidosis
48%
Sulfatase
23%
Glycosaminoglycan
19%
Sulfate
18%
N-Acetylgalactosamine
17%
Genome Editing
16%
Deficiency
15%
Fibroblast
15%
Komagataella pastoris
14%
Hexosaminidase
12%
Gene Therapy
11%
Lysosomal Storage Disease
11%
CRISPR
10%
Lysosome
9%
Recombinant
9%
Tay-Sachs Disease
8%
GM2 Gangliosidoses
7%
Reconstruction
7%
Enzyme Activity
7%
Methylotrophic Yeast
7%
Iduronate-2-Sulfatase
6%
Keratan Sulfate
6%
Escherichia coli
6%
Pharmacological Chaperone
6%
Amino Acids
6%
Komagataella
6%
Non-Viral Vector
5%
GM2 (Ganglioside)
5%
Arylsulfatase A
5%
Chondroitin
5%