Using Broadband Near-Infrared Spectroscopy to Track Multiple Chromophores: Applications in Dementia Diagnosis

Deepshikha Acharya; Emilia Butters; Alexander Caicedo; Li Su; John O’Brien; Gemma Bale

doi:10.1117/12.3097858

Using Broadband Near-Infrared Spectroscopy to Track Multiple Chromophores: Applications in Dementia Diagnosis

Deepshikha Acharya
, Emilia Butters
, Alexander Caicedo
, Li Su
, John O’Brien
, Gemma Bale

Department of Electronic Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Accurate dementia diagnosis requires tracking multiple biomarkers, increasing scan times and cost in an already limited MRI/PET environment. Here, we demonstrate broadband near-infrared spectroscopy as a potential alternative for simultaneous haemodynamic, metabolic and cerebrospinal-fluid tracking.

Original language	English
Title of host publication	Translational Biophotonics
Subtitle of host publication	Diagnostics and Therapeutics IV
Editors	Zhiwei Huang, Lothar D. Lilge
Publisher	SPIE
ISBN (Electronic)	9781510698055
DOIs	https://doi.org/10.1117/12.3097858
State	Published - 18 Dec 2025
Event	4th Translational Biophotonics: Diagnostics and Therapeutics - Munich, Germany Duration: 22 Jun 2025 → 26 Jun 2025

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	13934
ISSN (Print)	1605-7422

Conference

Conference	4th Translational Biophotonics: Diagnostics and Therapeutics
Country/Territory	Germany
City	Munich
Period	22/06/25 → 26/06/25

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10.1117/12.3097858

Cite this

Acharya, D., Butters, E., Caicedo, A., Su, L., O’Brien, J., & Bale, G. (2025). Using Broadband Near-Infrared Spectroscopy to Track Multiple Chromophores: Applications in Dementia Diagnosis. In Z. Huang, & L. D. Lilge (Eds.), Translational Biophotonics: Diagnostics and Therapeutics IV Article 139341K (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 13934). SPIE. https://doi.org/10.1117/12.3097858

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title = "Using Broadband Near-Infrared Spectroscopy to Track Multiple Chromophores: Applications in Dementia Diagnosis",

abstract = "Accurate dementia diagnosis requires tracking multiple biomarkers, increasing scan times and cost in an already limited MRI/PET environment. Here, we demonstrate broadband near-infrared spectroscopy as a potential alternative for simultaneous haemodynamic, metabolic and cerebrospinal-fluid tracking.",

author = "Deepshikha Acharya and Emilia Butters and Alexander Caicedo and Li Su and John O{\textquoteright}Brien and Gemma Bale",

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language = "English",

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Acharya, D, Butters, E, Caicedo, A, Su, L, O’Brien, J & Bale, G 2025, Using Broadband Near-Infrared Spectroscopy to Track Multiple Chromophores: Applications in Dementia Diagnosis. in Z Huang & LD Lilge (eds), Translational Biophotonics: Diagnostics and Therapeutics IV., 139341K, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 13934, SPIE, 4th Translational Biophotonics: Diagnostics and Therapeutics, Munich, Germany, 22/06/25. https://doi.org/10.1117/12.3097858

Using Broadband Near-Infrared Spectroscopy to Track Multiple Chromophores: Applications in Dementia Diagnosis. / Acharya, Deepshikha; Butters, Emilia; Caicedo, Alexander et al.
Translational Biophotonics: Diagnostics and Therapeutics IV. ed. / Zhiwei Huang; Lothar D. Lilge. SPIE, 2025. 139341K (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 13934).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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T1 - Using Broadband Near-Infrared Spectroscopy to Track Multiple Chromophores

T2 - 4th Translational Biophotonics: Diagnostics and Therapeutics

AU - Acharya, Deepshikha

AU - Butters, Emilia

AU - Caicedo, Alexander

AU - Su, Li

AU - O’Brien, John

AU - Bale, Gemma

PY - 2025/12/18

Y1 - 2025/12/18

N2 - Accurate dementia diagnosis requires tracking multiple biomarkers, increasing scan times and cost in an already limited MRI/PET environment. Here, we demonstrate broadband near-infrared spectroscopy as a potential alternative for simultaneous haemodynamic, metabolic and cerebrospinal-fluid tracking.

AB - Accurate dementia diagnosis requires tracking multiple biomarkers, increasing scan times and cost in an already limited MRI/PET environment. Here, we demonstrate broadband near-infrared spectroscopy as a potential alternative for simultaneous haemodynamic, metabolic and cerebrospinal-fluid tracking.

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DO - 10.1117/12.3097858

M3 - Conference contribution

AN - SCOPUS:105025968689

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Translational Biophotonics

A2 - Huang, Zhiwei

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PB - SPIE

Y2 - 22 June 2025 through 26 June 2025

ER -

Acharya D, Butters E, Caicedo A, Su L, O’Brien J, Bale G. Using Broadband Near-Infrared Spectroscopy to Track Multiple Chromophores: Applications in Dementia Diagnosis. In Huang Z, Lilge LD, editors, Translational Biophotonics: Diagnostics and Therapeutics IV. SPIE. 2025. 139341K. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.3097858

Using Broadband Near-Infrared Spectroscopy to Track Multiple Chromophores: Applications in Dementia Diagnosis

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