Abstract
Follicular lymphoma is a relatively indolent B-cell lymphoma composed of neoplastic centrocytes and centroblasts. The histologic transformation of follicular lymphoma is a well-described phenomenon with an average risk of 30% at ten years. The occurrence of Hodgkin lymphoma after follicular lymphoma, as well as composite lymphoma, is extremely rare. We report the case of a 79-year-old man with generalized lymphadenopathy who was diagnosed with follicular lymphoma and treated with six cycles of R-CHOP with a complete response. A lymph node biopsy three years later revealed persistent follicular lymphoma, after which the patient received radiotherapy. The patient returned with progressively enlarging axillary lymph nodes five years later. A lymph node biopsy demonstrated a composite lymphoma that was consistent with follicular lymphoma and Hodgkin lymphoma.
| Translated title of the contribution | Transformation of Follicular Lymphoma into Composite Lymphoma: A Case Report and Literature Review |
|---|---|
| Original language | Spanish |
| Pages (from-to) | 508-513 |
| Number of pages | 6 |
| Journal | Revista Medica de Chile |
| Volume | 152 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 2024 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Composite Lymphoma
- Epstein-Barr Virus
- Hodgkin Disease
- Human
- Immunohistochemistry
- Lymphoma, Follicular
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