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Transformación de un linfoma folicular a un linfoma compuesto. Reporte de un caso y revisión de la literatura

Translated title of the contribution: Transformation of Follicular Lymphoma into Composite Lymphoma: A Case Report and Literature Review

Research output: Contribution to journalReview articlepeer-review

Abstract

Follicular lymphoma is a relatively indolent B-cell lymphoma composed of neoplastic centrocytes and centroblasts. The histologic transformation of follicular lymphoma is a well-described phenomenon with an average risk of 30% at ten years. The occurrence of Hodgkin lymphoma after follicular lymphoma, as well as composite lymphoma, is extremely rare. We report the case of a 79-year-old man with generalized lymphadenopathy who was diagnosed with follicular lymphoma and treated with six cycles of R-CHOP with a complete response. A lymph node biopsy three years later revealed persistent follicular lymphoma, after which the patient received radiotherapy. The patient returned with progressively enlarging axillary lymph nodes five years later. A lymph node biopsy demonstrated a composite lymphoma that was consistent with follicular lymphoma and Hodgkin lymphoma.

Translated title of the contributionTransformation of Follicular Lymphoma into Composite Lymphoma: A Case Report and Literature Review
Original languageSpanish
Pages (from-to)508-513
Number of pages6
JournalRevista Medica de Chile
Volume152
Issue number4
DOIs
StatePublished - Apr 2024
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Composite Lymphoma
  • Epstein-Barr Virus
  • Hodgkin Disease
  • Human
  • Immunohistochemistry
  • Lymphoma, Follicular

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