Thyroid storm: Diagnostic and therapeutic approach

José Correa-Guerrero; Hugo Corrales Santander; Jorge Yepes Caro; Jesús Bello Simanca; Luis Rodríguez Arrieta; Alejandro Castellanos Pinedo; Elguis Rodríguez Garizabalo; Carmelo Dueñas Castell

doi:10.1016/j.acci.2024.10.010

Thyroid storm: Diagnostic and therapeutic approach

José Correa-Guerrero, Hugo Corrales Santander, Jorge Yepes Caro, Jesús Bello Simanca, Luis Rodríguez Arrieta, Alejandro Castellanos Pinedo, Elguis Rodríguez Garizabalo, Carmelo Dueñas Castell

Research output: Contribution to journal › Review article › peer-review

Abstract

Thyroid storm (TT) is a rare but potentially fatal condition if not detected and treated promptly. It is characterized by severe clinical manifestations at the level of the central nervous system, cardiovascular system, and gastrointestinal system, associated with elevated levels of free triiodothyronine (T3) and free thyroxine (T4). Infections and/or treatment discontinuation are the most frequent triggers. Identifying the triggering factor, reducing circulating levels of thyroid hormones, and admission to an intensive care unit become the cornerstone of treatment. In this review, based on a clinical scenario, we will provide information regarding the diagnostic and therapeutic approach to TT.

Translated title of the contribution	Tormenta tiroidea: abordaje diagnóstico y terapéutico
Original language	English
Pages (from-to)	159-173
Number of pages	15
Journal	Acta Colombiana de Cuidado Intensivo
Volume	25
Issue number	1
DOIs	https://doi.org/10.1016/j.acci.2024.10.010
State	Published - 01 Jan 2025
Externally published	Yes

Keywords

Antithyroid therapy
Endocrine emergency
Hyperthyroidism
Multiorgan dysfunction
Thyroid storm
Thyrotoxicosis

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10.1016/j.acci.2024.10.010

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title = "Thyroid storm: Diagnostic and therapeutic approach",

abstract = "Thyroid storm (TT) is a rare but potentially fatal condition if not detected and treated promptly. It is characterized by severe clinical manifestations at the level of the central nervous system, cardiovascular system, and gastrointestinal system, associated with elevated levels of free triiodothyronine (T3) and free thyroxine (T4). Infections and/or treatment discontinuation are the most frequent triggers. Identifying the triggering factor, reducing circulating levels of thyroid hormones, and admission to an intensive care unit become the cornerstone of treatment. In this review, based on a clinical scenario, we will provide information regarding the diagnostic and therapeutic approach to TT.",

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doi = "10.1016/j.acci.2024.10.010",

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T1 - Thyroid storm

T2 - Diagnostic and therapeutic approach

AU - Correa-Guerrero, José

AU - Corrales Santander, Hugo

AU - Yepes Caro, Jorge

AU - Bello Simanca, Jesús

AU - Rodríguez Arrieta, Luis

AU - Castellanos Pinedo, Alejandro

AU - Rodríguez Garizabalo, Elguis

AU - Dueñas Castell, Carmelo

PY - 2025/1/1

Y1 - 2025/1/1

N2 - Thyroid storm (TT) is a rare but potentially fatal condition if not detected and treated promptly. It is characterized by severe clinical manifestations at the level of the central nervous system, cardiovascular system, and gastrointestinal system, associated with elevated levels of free triiodothyronine (T3) and free thyroxine (T4). Infections and/or treatment discontinuation are the most frequent triggers. Identifying the triggering factor, reducing circulating levels of thyroid hormones, and admission to an intensive care unit become the cornerstone of treatment. In this review, based on a clinical scenario, we will provide information regarding the diagnostic and therapeutic approach to TT.

AB - Thyroid storm (TT) is a rare but potentially fatal condition if not detected and treated promptly. It is characterized by severe clinical manifestations at the level of the central nervous system, cardiovascular system, and gastrointestinal system, associated with elevated levels of free triiodothyronine (T3) and free thyroxine (T4). Infections and/or treatment discontinuation are the most frequent triggers. Identifying the triggering factor, reducing circulating levels of thyroid hormones, and admission to an intensive care unit become the cornerstone of treatment. In this review, based on a clinical scenario, we will provide information regarding the diagnostic and therapeutic approach to TT.

KW - Antithyroid therapy

KW - Endocrine emergency

KW - Hyperthyroidism

KW - Multiorgan dysfunction

KW - Thyroid storm

KW - Thyrotoxicosis

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U2 - 10.1016/j.acci.2024.10.010

DO - 10.1016/j.acci.2024.10.010

M3 - Review article

AN - SCOPUS:85210299969

SN - 0122-7262

VL - 25

SP - 159

EP - 173

JO - Acta Colombiana de Cuidado Intensivo

JF - Acta Colombiana de Cuidado Intensivo

IS - 1

ER -

Thyroid storm: Diagnostic and therapeutic approach

Abstract

Keywords

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