Therapeutic dilemma: alcohol withdrawal syndrome and concurrent hepatic encephalopathy. A case report

Alejandra López; Roberto Chavarría; Gabriel Oviedo

doi:10.1016/j.rcp.2019.10.002

Therapeutic dilemma: alcohol withdrawal syndrome and concurrent hepatic encephalopathy. A case report

Alejandra López
, Roberto Chavarría
, Gabriel Oviedo

Department of Psychiatry and Mental Health

Universidad de Costa Rica

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Alcohol use disorder is one of the main causes of morbidity and mortality in the world. Alcoholic liver disease is a common complication of this disorder, and hepatic encephalopathy is a serious complication of alcoholic cirrhosis. Precipitating factors may be related to infection, gastrointestinal bleeding, dehydration or the effects of psychotropic drugs (e.g. benzodiazepines and non-benzodiazepine hypnotics). We present a case of the hospital management of a patient with a severe alcohol use disorder, cirrhosis and hepatic encephalopathy who developed alcohol withdrawal symptoms while in hospital, and discuss the complexity of the antagonistic management of a GABAergic delirium characteristic of hepatic encephalopathy in the context of a glutamatergic-noradrenergic delirium due to alcohol withdrawal.

Translated title of the contribution	Dilema terapéutico: síndrome de abstinencia alcohólica y encefalopatía hepática concurrentes. A propósito de un caso
Original language	English
Pages (from-to)	52-56
Number of pages	5
Journal	Revista Colombiana de Psiquiatria
Volume	50
Issue number	1
DOIs	https://doi.org/10.1016/j.rcp.2019.10.002
State	Published - 01 Jan 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Alcohol withdrawal
CIWA-Ar
Delirium tremens
Hepatic encephalopathy

Access to Document

10.1016/j.rcp.2019.10.002

Cite this

@article{8f0d13f8fbd6473f8b0db95ece5cb034,

title = "Therapeutic dilemma: alcohol withdrawal syndrome and concurrent hepatic encephalopathy. A case report",

abstract = "Alcohol use disorder is one of the main causes of morbidity and mortality in the world. Alcoholic liver disease is a common complication of this disorder, and hepatic encephalopathy is a serious complication of alcoholic cirrhosis. Precipitating factors may be related to infection, gastrointestinal bleeding, dehydration or the effects of psychotropic drugs (e.g. benzodiazepines and non-benzodiazepine hypnotics). We present a case of the hospital management of a patient with a severe alcohol use disorder, cirrhosis and hepatic encephalopathy who developed alcohol withdrawal symptoms while in hospital, and discuss the complexity of the antagonistic management of a GABAergic delirium characteristic of hepatic encephalopathy in the context of a glutamatergic-noradrenergic delirium due to alcohol withdrawal.",

keywords = "Alcohol withdrawal, CIWA-Ar, Delirium tremens, Hepatic encephalopathy",

author = "Alejandra L{\'o}pez and Roberto Chavarr{\'i}a and Gabriel Oviedo",

note = "Publisher Copyright: {\textcopyright} 2019 Asociaci{\'o}n Colombiana de Psiquiatr{\'i}a",

year = "2021",

month = jan,

day = "1",

doi = "10.1016/j.rcp.2019.10.002",

language = "English",

volume = "50",

pages = "52--56",

journal = "Revista Colombiana de Psiquiatria",

issn = "0034-7450",

publisher = "Asociacion Colombiana de Psiquiatria",

number = "1",

}

TY - JOUR

T1 - Therapeutic dilemma

T2 - alcohol withdrawal syndrome and concurrent hepatic encephalopathy. A case report

AU - López, Alejandra

AU - Chavarría, Roberto

AU - Oviedo, Gabriel

PY - 2021/1/1

Y1 - 2021/1/1

N2 - Alcohol use disorder is one of the main causes of morbidity and mortality in the world. Alcoholic liver disease is a common complication of this disorder, and hepatic encephalopathy is a serious complication of alcoholic cirrhosis. Precipitating factors may be related to infection, gastrointestinal bleeding, dehydration or the effects of psychotropic drugs (e.g. benzodiazepines and non-benzodiazepine hypnotics). We present a case of the hospital management of a patient with a severe alcohol use disorder, cirrhosis and hepatic encephalopathy who developed alcohol withdrawal symptoms while in hospital, and discuss the complexity of the antagonistic management of a GABAergic delirium characteristic of hepatic encephalopathy in the context of a glutamatergic-noradrenergic delirium due to alcohol withdrawal.

AB - Alcohol use disorder is one of the main causes of morbidity and mortality in the world. Alcoholic liver disease is a common complication of this disorder, and hepatic encephalopathy is a serious complication of alcoholic cirrhosis. Precipitating factors may be related to infection, gastrointestinal bleeding, dehydration or the effects of psychotropic drugs (e.g. benzodiazepines and non-benzodiazepine hypnotics). We present a case of the hospital management of a patient with a severe alcohol use disorder, cirrhosis and hepatic encephalopathy who developed alcohol withdrawal symptoms while in hospital, and discuss the complexity of the antagonistic management of a GABAergic delirium characteristic of hepatic encephalopathy in the context of a glutamatergic-noradrenergic delirium due to alcohol withdrawal.

KW - Alcohol withdrawal

KW - CIWA-Ar

KW - Delirium tremens

KW - Hepatic encephalopathy

UR - https://www.scopus.com/pages/publications/85078120861

U2 - 10.1016/j.rcp.2019.10.002

DO - 10.1016/j.rcp.2019.10.002

M3 - Article

C2 - 33648698

AN - SCOPUS:85078120861

SN - 0034-7450

VL - 50

SP - 52

EP - 56

JO - Revista Colombiana de Psiquiatria

JF - Revista Colombiana de Psiquiatria

IS - 1

ER -

Therapeutic dilemma: alcohol withdrawal syndrome and concurrent hepatic encephalopathy. A case report

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this