TY - JOUR
T1 - Systemic lupus erythematosus/ANCA-associated vasculitis overlap
T2 - An explanation for atypical lupus manifestation
AU - Botero B, Juan D.
AU - Bernal-Macías, Santiago
AU - Celis P, Carlos A.
AU - Lasso A, Javier I.
AU - Rodríguez, Jorge
AU - Arias Álvarez, Liliana
AU - Gonzalez, Catalina
AU - Contreras, Kateir M.
AU - Fernández-Ávila, Daniel G.
N1 - Publisher Copyright:
© The Author(s) 2022.
PY - 2022/4
Y1 - 2022/4
N2 - The coexistence of systemic lupus erythematosus (SLE) and ANCA-associated vasculitis (AAV) as an overlapping syndrome is not common. Here, we report a case of a 33-year-old woman, with recent SLE diagnosis due to skin, kidney, articular, and immunologic compromise, in whom a chest CT scan showed bilateral nodules, consolidations, and tree-in-bud pattern; thoracoscopic lung biopsy revealed diffuse non-caseating granulomas, without other features of sarcoid, organizing pneumonia, or hypersensitivity pneumonitis with high positive p-ANCA titers. Overlap between SLE and AAV was a possible explanation for lupus granulomatous pneumonitis, and for this reason, a multidisciplinary meeting was held to evaluate complex patients with interstitial lung diseases patients.
AB - The coexistence of systemic lupus erythematosus (SLE) and ANCA-associated vasculitis (AAV) as an overlapping syndrome is not common. Here, we report a case of a 33-year-old woman, with recent SLE diagnosis due to skin, kidney, articular, and immunologic compromise, in whom a chest CT scan showed bilateral nodules, consolidations, and tree-in-bud pattern; thoracoscopic lung biopsy revealed diffuse non-caseating granulomas, without other features of sarcoid, organizing pneumonia, or hypersensitivity pneumonitis with high positive p-ANCA titers. Overlap between SLE and AAV was a possible explanation for lupus granulomatous pneumonitis, and for this reason, a multidisciplinary meeting was held to evaluate complex patients with interstitial lung diseases patients.
KW - ANCA-Associated Vasculitis
KW - Granulomatosis with Polyangiitis
KW - Interstitial Lung Diseases
KW - Systemic Lupus Erythematosus
UR - http://www.scopus.com/inward/record.url?scp=85126047458&partnerID=8YFLogxK
U2 - 10.1177/09612033221084519
DO - 10.1177/09612033221084519
M3 - Article
C2 - 35244473
AN - SCOPUS:85126047458
SN - 0961-2033
VL - 31
SP - 495
EP - 499
JO - Lupus
JF - Lupus
IS - 4
ER -