SYNTHETIC OLIGOPEPTIDES DESIGNED FROM MITE CYSTEINE PROTEASES AND METHODS FOR THE PRODUCTION OF IGY POLYCLONAL ANTIBODIES FOR THE DETECTION OF INTRADOMICILIARY MITES

Eduardo Egea; Luis Alejandro Barrera Avellaneda; Angela Johana Espejo Mojica; Angela Catalina Sosa Molano; Elkin Navarro; Gloria Garavito; Luz Dary  Mendoza

SYNTHETIC OLIGOPEPTIDES DESIGNED FROM MITE CYSTEINE PROTEASES AND METHODS FOR THE PRODUCTION OF IGY POLYCLONAL ANTIBODIES FOR THE DETECTION OF INTRADOMICILIARY MITES

Eduardo Egea (Inventor)
, Luis Alejandro Barrera Avellaneda (Inventor)
, Angela Johana Espejo Mojica (Inventor)
, Angela Catalina Sosa Molano (Inventor)
, Elkin Navarro (Inventor)
, Gloria Garavito (Inventor)
, Luz Dary Mendoza (Inventor)

Universidad del Norte

Research output: Innovation Products › Invention patent

Abstract

The invention refers to the design, synthesis and evaluation of 6 synthetic oligopeptides, that have not been previously described, designed from the T and B epitopes of allergens of group I of intradomiciliary mites of the species Dermatophagoides pteronyssinus, Dermatophagoides farinae and Blomia tropicalis, which can be used in the immunomodulation of individuals having immunocompetent systems and in the production of IgY polyclonal antibodies. The invention relates to a first method for obtaining a composition of IgY polyclonal antibodies that can be used as a diagnostic reagent having low cost and high reactivity in respect of intradomiciliary mites, and a second method for the detection of mite allergens, using the IgY antibody composition developed in the first method. The invention further relates to the composition of the IgY polyclonal antibodies.

Original language	English
Publication/registration number	EP2431381
International Classification	C07K 16/ 18 A I
Grant date	17/03/10
Filing date	19/09/11
State	Published - 05 Aug 2015

Cite this

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title = "SYNTHETIC OLIGOPEPTIDES DESIGNED FROM MITE CYSTEINE PROTEASES AND METHODS FOR THE PRODUCTION OF IGY POLYCLONAL ANTIBODIES FOR THE DETECTION OF INTRADOMICILIARY MITES",

abstract = "The invention refers to the design, synthesis and evaluation of 6 synthetic oligopeptides, that have not been previously described, designed from the T and B epitopes of allergens of group I of intradomiciliary mites of the species Dermatophagoides pteronyssinus, Dermatophagoides farinae and Blomia tropicalis, which can be used in the immunomodulation of individuals having immunocompetent systems and in the production of IgY polyclonal antibodies. The invention relates to a first method for obtaining a composition of IgY polyclonal antibodies that can be used as a diagnostic reagent having low cost and high reactivity in respect of intradomiciliary mites, and a second method for the detection of mite allergens, using the IgY antibody composition developed in the first method. The invention further relates to the composition of the IgY polyclonal antibodies.",

author = "Eduardo Egea and \{Barrera Avellaneda\}, \{Luis Alejandro\} and \{Espejo Mojica\}, \{Angela Johana\} and \{Sosa Molano\}, \{Angela Catalina\} and Elkin Navarro and Gloria Garavito and Mendoza, \{Luz Dary\}",

year = "2015",

month = aug,

day = "5",

language = "English",

type = "Patent",

note = "EP2431381; C07K 16/ 18 A I",

}

SYNTHETIC OLIGOPEPTIDES DESIGNED FROM MITE CYSTEINE PROTEASES AND METHODS FOR THE PRODUCTION OF IGY POLYCLONAL ANTIBODIES FOR THE DETECTION OF INTRADOMICILIARY MITES. / Egea, Eduardo (Inventor); Barrera Avellaneda, Luis Alejandro (Inventor); Espejo Mojica, Angela Johana (Inventor) et al.
Patent No.: EP2431381. Aug 05, 2015.

Research output: Innovation Products › Invention patent

TY - PAT

T1 - SYNTHETIC OLIGOPEPTIDES DESIGNED FROM MITE CYSTEINE PROTEASES AND METHODS FOR THE PRODUCTION OF IGY POLYCLONAL ANTIBODIES FOR THE DETECTION OF INTRADOMICILIARY MITES

AU - Egea, Eduardo

AU - Barrera Avellaneda, Luis Alejandro

AU - Espejo Mojica, Angela Johana

AU - Sosa Molano, Angela Catalina

AU - Navarro, Elkin

AU - Garavito, Gloria

AU - Mendoza, Luz Dary

PY - 2015/8/5

Y1 - 2015/8/5

N2 - The invention refers to the design, synthesis and evaluation of 6 synthetic oligopeptides, that have not been previously described, designed from the T and B epitopes of allergens of group I of intradomiciliary mites of the species Dermatophagoides pteronyssinus, Dermatophagoides farinae and Blomia tropicalis, which can be used in the immunomodulation of individuals having immunocompetent systems and in the production of IgY polyclonal antibodies. The invention relates to a first method for obtaining a composition of IgY polyclonal antibodies that can be used as a diagnostic reagent having low cost and high reactivity in respect of intradomiciliary mites, and a second method for the detection of mite allergens, using the IgY antibody composition developed in the first method. The invention further relates to the composition of the IgY polyclonal antibodies.

AB - The invention refers to the design, synthesis and evaluation of 6 synthetic oligopeptides, that have not been previously described, designed from the T and B epitopes of allergens of group I of intradomiciliary mites of the species Dermatophagoides pteronyssinus, Dermatophagoides farinae and Blomia tropicalis, which can be used in the immunomodulation of individuals having immunocompetent systems and in the production of IgY polyclonal antibodies. The invention relates to a first method for obtaining a composition of IgY polyclonal antibodies that can be used as a diagnostic reagent having low cost and high reactivity in respect of intradomiciliary mites, and a second method for the detection of mite allergens, using the IgY antibody composition developed in the first method. The invention further relates to the composition of the IgY polyclonal antibodies.

UR - https://worldwide.espacenet.com/patent/search/family/043356819/publication/EP2431381A2?q=EP2431381

M3 - Invention patent

M1 - EP2431381

Y2 - 2011/09/19

ER -

SYNTHETIC OLIGOPEPTIDES DESIGNED FROM MITE CYSTEINE PROTEASES AND METHODS FOR THE PRODUCTION OF IGY POLYCLONAL ANTIBODIES FOR THE DETECTION OF INTRADOMICILIARY MITES

Abstract

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