Synthesis of high crystallinity biphasic calcium phosphates/gold nanoparticles composites by solution combustion method with antimicrobial response

Alex Lopera, Edgar Andrés Chavarriaga, Vinicius D.N. Bezzon, Mateo Zutta, Adrián Gómez, Jorge Puerta, Sara Maria Robledo, Victoria E. Ospina, Carlos Paucar, Claudia Garcia

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Calcium phosphates are biomaterials widely used in bone tissue engineering. In recent years, the alternative of obtaining these materials with antimicrobial properties, has been explored due to the multiple advantages that this would imply in the design of devices or implants that prevent the failure of these associated with bacterial colonization. The goal of the present work was obtaining gold nanoparticles supported on biphasic calcium phosphates (BCPs) with high crystallinity by one-step solution combustion technique, and with antimicrobial response, a fact that can significantly reduce the production cost of these materials. X-ray diffractograms (XRD) showed that prepared powders have high crystallinity owing to high temperatures during the combustion reaction, also Rietveld refinement showed that the inclusion of gold nanoparticles (AuNPs) influenced the phases' ratio obtained. Furthermore, scanning electron microscopy (SEM) showed agglomeration of particles with morphologies with shape tending to be equigranular, while the presence of AuNPs was corroborated by transmission electron microscopy (TEM). All samples that were obtained in a single step, by solution combustion, showed antimicrobial behavior validated through the inhibition halos, whereas particles subjected to thermal treatment lost their antimicrobial response.

Translated title of the contributionSíntesis de materiales compuestos de fosfatos de calcio bifásicos/nanopartículas de oro de elevada cristalinidad, mediante el método de combustión de soluciones, con respuesta antimicrobiana
Original languageEnglish
Pages (from-to)487-497
Number of pages11
JournalBoletin de la Sociedad Espanola de Ceramica y Vidrio
Volume61
Issue number5
DOIs
StatePublished - Sep 2022

Keywords

  • Antimicrobial
  • Biphasic calcium phosphates
  • Gold nanoparticles
  • High crystallinity
  • Solution combustion synthesis

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