TY - JOUR
T1 - Six-year multicenter study on short-term peripheral venous catheters-related bloodstream infection rates in 727 intensive care units of 268 hospitals in 141 cities of 42 countries of Africa, the Americas, Eastern Mediterranean, Europe, South East Asia, and Western Pacific Regions
T2 - International Nosocomial Infection Control Consortium (INICC) findings
AU - Rosenthal, Victor Daniel
AU - Bat-Erdene, Ider
AU - Gupta, Debkishore
AU - Belkebir, Souad
AU - Rajhans, Prasad
AU - Zand, Farid
AU - Myatra, Sheila Nainan
AU - Afeef, Majeda
AU - Tanzi, Vito L.
AU - Muralidharan, S.
AU - Al-Abdely, Hail M.
AU - El-Kholy, Amani
AU - AlKhawaja, Safa A. Aziz
AU - Demiroz, Ali Pekcan
AU - Mehta, Yatin
AU - Rai, Vineya
AU - Hung, Nguyen Viet
AU - Sayed, Amani F.
AU - Salgado-Yepez, Estuardo
AU - Elahi, Naheed
AU - del Rayo Morfin-Otero, Maria
AU - Luxsuwong, Montri
AU - De-Carvalho, Braulio Matias
AU - Tapang, Audrey Rose D.
AU - Velinova, Velmira Angelova
AU - Quesada-Mora, Ana Marcela
AU - Anguseva, Tanja
AU - Ikram, Aamer
AU - Aguilar-de-Moros, Daisy
AU - Duszynska, Wieslawa
AU - Mejia, Nepomuceno
AU - Horhat, Florin George
AU - Belskiy, Vladislav
AU - Mioljevic, Vesna
AU - Di-Silvestre, Gabriela
AU - Furova, Katarina
AU - Gamar-Elanbya, May Osman
AU - Gupta, Umesh
AU - Abidi, Khalid
AU - Raka, Lul
AU - Guo, Xiuqin
AU - Jayatilleke, Kushlani
AU - Ben-Jaballah, Najla
AU - Sandoval-Castillo, Harrison Ronald
AU - Trotter, Andrew
AU - Valderrama-Beltran, Sandra L.
AU - Leblebicioglu, Hakan
AU - Guanche-Garcell, Humberto
AU - de Lourdes-Duenas, Miriam
PY - 2020/5
Y1 - 2020/5
N2 - Background: Short-term peripheral venous catheter-related bloodstream infection (PVCR-BSI) rates have not been systematically studied in resource-limited countries, and data on their incidence by number of device days are not available. Methods: Prospective, surveillance study on PVCR-BSI conducted from September 1, 2013, to May 31, 2019, in 727 intensive care units (ICUs), by members of the International Nosocomial Infection Control Consortium (INICC), from 268 hospitals in 141 cities of 42 countries of Africa, the Americas, Eastern Mediterranean, Europe, South East Asia, and Western Pacific regions. For this research, we applied definition and criteria of the CDC NHSN, methodology of the INICC, and software named INICC Surveillance Online System. Results: We followed 149,609 ICU patients for 731,135 bed days and 743,508 short-term peripheral venous catheter (PVC) days. We identified 1,789 PVCR-BSIs for an overall rate of 2.41 per 1,000 PVC days. Mortality in patients with PVC but without PVCR-BSI was 6.67%, and mortality was 18% in patients with PVC and PVCR-BSI. The length of stay of patients with PVC but without PVCR-BSI was 4.83 days, and the length of stay was 9.85 days in patients with PVC and PVCR-BSI. Among these infections, the microorganism profile showed 58% gram-negative bacteria: Escherichia coli (16%), Klebsiella spp (11%), Pseudomonas aeruginosa (6%), Enterobacter spp (4%), and others (20%) including Serratia marcescens. Staphylococcus aureus were the predominant gram-positive bacteria (12%). Conclusions: PVCR-BSI rates in INICC ICUs were much higher than rates published from industrialized countries. Infection prevention programs must be implemented to reduce the incidence of PVCR-BSIs in resource-limited countries.
AB - Background: Short-term peripheral venous catheter-related bloodstream infection (PVCR-BSI) rates have not been systematically studied in resource-limited countries, and data on their incidence by number of device days are not available. Methods: Prospective, surveillance study on PVCR-BSI conducted from September 1, 2013, to May 31, 2019, in 727 intensive care units (ICUs), by members of the International Nosocomial Infection Control Consortium (INICC), from 268 hospitals in 141 cities of 42 countries of Africa, the Americas, Eastern Mediterranean, Europe, South East Asia, and Western Pacific regions. For this research, we applied definition and criteria of the CDC NHSN, methodology of the INICC, and software named INICC Surveillance Online System. Results: We followed 149,609 ICU patients for 731,135 bed days and 743,508 short-term peripheral venous catheter (PVC) days. We identified 1,789 PVCR-BSIs for an overall rate of 2.41 per 1,000 PVC days. Mortality in patients with PVC but without PVCR-BSI was 6.67%, and mortality was 18% in patients with PVC and PVCR-BSI. The length of stay of patients with PVC but without PVCR-BSI was 4.83 days, and the length of stay was 9.85 days in patients with PVC and PVCR-BSI. Among these infections, the microorganism profile showed 58% gram-negative bacteria: Escherichia coli (16%), Klebsiella spp (11%), Pseudomonas aeruginosa (6%), Enterobacter spp (4%), and others (20%) including Serratia marcescens. Staphylococcus aureus were the predominant gram-positive bacteria (12%). Conclusions: PVCR-BSI rates in INICC ICUs were much higher than rates published from industrialized countries. Infection prevention programs must be implemented to reduce the incidence of PVCR-BSIs in resource-limited countries.
KW - VENTILATOR-ASSOCIATED PNEUMONIA
KW - DEVICE-ASSOCIATED INFECTIONS
KW - MULTIDIMENSIONAL APPROACH
KW - SOCIOECONOMIC IMPACT
KW - CONTROL STRATEGY
KW - PREVENTION
KW - IMPLEMENTATION
KW - INTERVENTION
KW - BUNDLE
KW - RISK
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=pure_puj3&SrcAuth=WosAPI&KeyUT=WOS:000530066000010&DestLinkType=FullRecord&DestApp=WOS_CPL
UR - https://www.researchgate.net/publication/340005368_Six-year_multicenter_study_on_short-term_peripheral_venous_catheters-related_bloodstream_infection_rates_in_727_intensive_care_units_of_268_hospitals_in_141_cities_of_42_countries_of_Africa_the_Americ
U2 - 10.1017/ice.2020.20
DO - 10.1017/ice.2020.20
M3 - Article
C2 - 32183925
SN - 0899-823X
VL - 41
SP - 553
EP - 563
JO - Infection Control and Hospital Epidemiology
JF - Infection Control and Hospital Epidemiology
IS - 5
M1 - PII S0899823X20000203
ER -