TY - JOUR
T1 - Regenerative characteristics of the immortal jellyfish, Turritopsis dohrnii, and their potential implications for human aging
AU - Velasco-Muñoz, Valentina
AU - Uribe-Gaviria, Mateo
AU - Suárez-Gómez, Santiago Andrés
AU - Villamizar-Romero, Antonio
AU - Ricaurte-Fajardo, Andrés
AU - Vásquez-Vélez, Isabel Cristina
AU - Cano-Gutiérrez, Carlos A.
N1 - Publisher Copyright:
© 2024 SEGG
PY - 2025/5/1
Y1 - 2025/5/1
N2 - The jellyfish Turritopsis dohrnii (T. Nutricala) is a cnidarian of the Oceaniidae family that lives in the Mediterranean Sea. It is known as the immortal jellyfish since, through a process of cell development called transdifferentiation, it manages to return to a polyp state. The role of regeneration processes and their impact on aging have been studied in recent years for their potential applications in the development of more efficient pharmacology to address disorders related to aging. Reviewing the terms related to transdifferentiation in jellyfish and understanding the underlying mechanisms can help comprehend diverse processes such as aging, regeneration, and the molecular bases of diseases like cancer. This paper's purpose is to provide a description of the regenerative characteristics of the jellyfish T. dohrnii, investigate how its regenerative processes allow it to rejuvenate, and determine if these tissue restoration processes are also found in humans.
AB - The jellyfish Turritopsis dohrnii (T. Nutricala) is a cnidarian of the Oceaniidae family that lives in the Mediterranean Sea. It is known as the immortal jellyfish since, through a process of cell development called transdifferentiation, it manages to return to a polyp state. The role of regeneration processes and their impact on aging have been studied in recent years for their potential applications in the development of more efficient pharmacology to address disorders related to aging. Reviewing the terms related to transdifferentiation in jellyfish and understanding the underlying mechanisms can help comprehend diverse processes such as aging, regeneration, and the molecular bases of diseases like cancer. This paper's purpose is to provide a description of the regenerative characteristics of the jellyfish T. dohrnii, investigate how its regenerative processes allow it to rejuvenate, and determine if these tissue restoration processes are also found in humans.
KW - Aging
KW - Regeneration
KW - Transdifferentiation
KW - Turritopsis dohrnii
UR - http://www.scopus.com/inward/record.url?scp=85212872557&partnerID=8YFLogxK
U2 - 10.1016/j.regg.2024.101607
DO - 10.1016/j.regg.2024.101607
M3 - Review article
AN - SCOPUS:85212872557
SN - 0211-139X
VL - 60
JO - Revista Espanola de Geriatria y Gerontologia
JF - Revista Espanola de Geriatria y Gerontologia
IS - 3
M1 - 101607
ER -
