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Recognition of brain structures from MER-signals using dynamic MFCC analysis and a HMC classifier

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

A novel methodology for the characterization of Microelectrode Recording signals (MER-signals) in Parkinson's patients in order to recognize basal ganglia in the brain is presented in this work. The most common approach of MER signals analysis consists of time-frequency analysis through Short Time Fourier Transform, Wavelet Transform, or Filters Banks. We present an approach based on MEL-Frequency Cepstral Coefficients (MFCC) and K-means clustering to obtain dynamic features from MER-signals. A Hidden Markov Chain (HMC) with 1, 2, 3, and 4 states was used for the classification of four classes of basal ganglia: Thalamus (Tal), Zone Incerta (ZI), Subthalamic Nucleus (STN) and Substantia Nigra reticulata (SNr), achieving a positive identification over 82%. A performance analysis for each HHM model is presented using ROC curves.

Original languageEnglish
Title of host publication13th Mediterranean Conference on Medical and Biological Engineering and Computing 2013 - MEDICON 2013
PublisherSpringer Verlag
Pages742-745
Number of pages4
ISBN (Print)9783319008455
DOIs
StatePublished - 2014
Externally publishedYes
Event13th Mediterranean Conference on Medical and Biological Engineering and Computing 2013, MEDICON 2013 - Seville, Spain
Duration: 25 Sep 201328 Sep 2013

Publication series

NameIFMBE Proceedings
Volume41
ISSN (Print)1680-0737

Conference

Conference13th Mediterranean Conference on Medical and Biological Engineering and Computing 2013, MEDICON 2013
Country/TerritorySpain
CitySeville
Period25/09/1328/09/13

Keywords

  • Dynamic features
  • Hidden Markov Chain (HMC)
  • MEL-Frequency cepstral coefficients (MFCC)
  • MER signals
  • Parkinson's disease

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