TY - JOUR
T1 - Proximal femoral growth plate mechanical behavior
T2 - Comparison between different developmental stages
AU - Castro-Abril, Héctor Alfonso
AU - Gutiérrez, María Lucía
AU - Garzón-Alvarado, Diego Alexander
N1 - Publisher Copyright:
© 2016 Elsevier Ltd
PY - 2016/9/1
Y1 - 2016/9/1
N2 - In long bones the growth plate is a cartilaginous structure located between the epiphysis and the diaphysis. This structure regulates longitudinal growth and helps determine the structure of mature bone through the process of endochondral ossification. During human growth the femur's proximal growth plate experiences changes in its morphology that may be related to its mechanical environment. Thus, in order to test this hypothesis from a computational perspective, a finite element analysis on a proximal femur was performed on which we modeled different physeal geometries corresponding to the shapes acquired for this structure in a child between the ages of five to eleven. Results show augmented Von Mises stress values with increasing irregularities in physeal geometry, whereas displacement decreased with increased irregularities in the growth plate's morphology. Such observations suggest that growth plate's shape changes follows a possible mechanical adaptation on imposed loads to sustain a person's increasing body mass during growth.
AB - In long bones the growth plate is a cartilaginous structure located between the epiphysis and the diaphysis. This structure regulates longitudinal growth and helps determine the structure of mature bone through the process of endochondral ossification. During human growth the femur's proximal growth plate experiences changes in its morphology that may be related to its mechanical environment. Thus, in order to test this hypothesis from a computational perspective, a finite element analysis on a proximal femur was performed on which we modeled different physeal geometries corresponding to the shapes acquired for this structure in a child between the ages of five to eleven. Results show augmented Von Mises stress values with increasing irregularities in physeal geometry, whereas displacement decreased with increased irregularities in the growth plate's morphology. Such observations suggest that growth plate's shape changes follows a possible mechanical adaptation on imposed loads to sustain a person's increasing body mass during growth.
KW - Finite element analysis
KW - Growth plate
KW - Growth plate development
KW - Von Mises stress
UR - http://www.scopus.com/inward/record.url?scp=84979892927&partnerID=8YFLogxK
U2 - 10.1016/j.compbiomed.2016.07.011
DO - 10.1016/j.compbiomed.2016.07.011
M3 - Article
C2 - 27479492
AN - SCOPUS:84979892927
SN - 0010-4825
VL - 76
SP - 192
EP - 201
JO - Computers in Biology and Medicine
JF - Computers in Biology and Medicine
ER -