Abstract
Previous studies have demonstrated that Physalis peruviana has antioxidant, antiinflammatory, antidiabetic, and hepatic protective effects. The present work aimed to perform different assays to get a deeper insight into the antioxidant activity of the hydroethanolic extract of calyces from P. peruviana (HEPP) and its fractions. 2,2-Diphenyl-1-picrylhydrazyl (DPPH·) scavenging, lipid peroxidation, low-density lipoprotein cholesterol (LDL-c), and advanced products of glycation (AGEs) were measured. Results showed that the HEPP and its butanol fraction (BFPP) displayed DPPH· radical scavenging activities with IC50 values of 29.9 and 51.4µg/mL, respectively. Similar results were obtained when the diene formation was induced in LDL-c: IC50 values of 211.2 and 103.0µg/mL, for HEPP and BFPP, respectively. HEPP, BFPP and EFPP showed antiglycation activity with IC50 of 141.1, 183.0, and 226.7µg/mL, respectively. In sum, HEPP and BFPP have the potential to prevent tissues from free radicals and thereby protect the cellular membranes from lipid peroxidation.
| Original language | English |
|---|---|
| Title of host publication | Handbook of Goldenberry (Physalis peruviana) |
| Subtitle of host publication | Cultivation, Processing, Chemistry, and Functionality |
| Publisher | Elsevier |
| Pages | 447-454 |
| Number of pages | 8 |
| ISBN (Electronic) | 9780443154331 |
| ISBN (Print) | 9780443154348 |
| DOIs | |
| State | Published - 01 Jan 2024 |
Keywords
- Food products
- biochemistry applications, food analysis
- pharmaceutical chemistry
- pharmacological parameter
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