Novel VIM metallo-β-lactamase variant, VIM-24, from a Klebsiella pneumoniae isolate from Colombia

Maria Camila Montealegre; Adriana Correa; David F. Briceño; Natalia C. Rosas; Elsa De La Cadena; Sory J. Ruiz; Maria F. Mojica; Ruben Dario Camargo; Ivan Zuluaga; Adriana Marin; John P. Quinn; Maria Virginia Villegas; Henry Mendoza; Flor Angela Cubides; Martha Patricia Melendez; Luz Angelica Quintero; Ilba Liliana Galeano; Beatriz Porras; Guillermo Ortiz; Luz Mila Lopez; Henry Oliveros; Maria Nilse Gonzalez; Angela Pescador; Monica Ballesteros; Sandra Valderrama; Alirio Rodriguez; Jairo Perez; Carlos Ignacio Gomez; Jaime Lopez; Jorge Donado; Monica Cuartas; Ana Lucia Correa; Lina Marcela Castañeda; Julian Betancourth; Juan David Villa; Jorge Nagles; Nancy Estella Gonzalez; Magda Orjuela; Ana Cristina Quiroga; Rodrigo Agudelo; Carolina Rios; Martha Vallejo; Luz Marina Melguizo; Dora Rivas; Sergio Velez; Ernesto Martinez; Jose Millan Oñate; Christian Pallares; Luz Marina Gallardo; Alba Lucia Bohorques; Nancy Villamarin; Fernando Rosso; Juan Diego Velez; Jose Garcia; Monica Recalde; Alejandra Toala; John Jairo Echeverry; Beatriz Lopez; Claudia Barcenas; Karol Monsalve; Luis Angel Villar; Mayerly Anaya; Agustin Vega; Miriam Fanny Amaya; Matha Jacome; Rocio Abaunza; Martin Mejía; Angela Mendoza; Carmen Elisa Llano; Myriam Gomez; Rodolfo Cabrales; Amparo Ovalle; Claudia Echeverry; M. Del Rosario Aldana; Pablo Lopez; Luis Gonzalez

doi:10.1128/AAC.01208-10

Novel VIM metallo-β-lactamase variant, VIM-24, from a Klebsiella pneumoniae isolate from Colombia

Maria Camila Montealegre
, Adriana Correa
, David F. Briceño
, Natalia C. Rosas
, Elsa De La Cadena
, Sory J. Ruiz
, Maria F. Mojica
, Ruben Dario Camargo
, Ivan Zuluaga
, Adriana Marin
, John P. Quinn
, Maria Virginia Villegas
, Henry Mendoza
, Flor Angela Cubides
, Martha Patricia Melendez
, Luz Angelica Quintero
, Ilba Liliana Galeano
, Beatriz Porras
, Guillermo Ortiz
, Luz Mila Lopez

Henry Oliveros, Maria Nilse Gonzalez, Angela Pescador, Monica Ballesteros, Sandra Valderrama, Alirio Rodriguez, Jairo Perez, Carlos Ignacio Gomez, Jaime Lopez, Jorge Donado, Monica Cuartas, Ana Lucia Correa, Lina Marcela Castañeda, Julian Betancourth, Juan David Villa, Jorge Nagles, Nancy Estella Gonzalez, Magda Orjuela, Ana Cristina Quiroga, Rodrigo Agudelo, Carolina Rios, Martha Vallejo, Luz Marina Melguizo, Dora Rivas, Sergio Velez, Ernesto Martinez, Jose Millan Oñate, Christian Pallares, Luz Marina Gallardo, Alba Lucia Bohorques, Nancy Villamarin, Fernando Rosso, Juan Diego Velez, Jose Garcia, Monica Recalde, Alejandra Toala, John Jairo Echeverry, Beatriz Lopez, Claudia Barcenas, Karol Monsalve, Luis Angel Villar, Mayerly Anaya, Agustin Vega, Miriam Fanny Amaya, Matha Jacome, Rocio Abaunza, Martin Mejía, Angela Mendoza, Carmen Elisa Llano, Myriam Gomez, Rodolfo Cabrales, Amparo Ovalle, Claudia Echeverry, M. Del Rosario Aldana, Pablo Lopez, Luis Gonzalez

International Center for Medical Research and Training (CIDEIM)
Clínica General del Norte
Pfizer Global Research and Development
Hospital Central de la Policia
Hospital Santa Clara
Hospital Militar Central
Hospital Pablo Tobon Uribe
Clínica de Las Américas
Hospital General de Medellín
Hospital Universitario del Valle
Fundación Valle del Lili
La Foscal
Fundación Cardiovascular
Hospital Universitario de Santander
Hospital Universitario San Jorge
Hospital Federico Lleras Acosta

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

We report the emergence of a novel VIM variant (VIM-24) in a Klebsiella pneumoniae isolate in Colombia. The isolate displays MICs for carbapenems below the resistance breakpoints, posing a real challenge for its detection. The blaVIM-24 gene was located within a class 1 integron carried on a large plasmid. Further studies are needed to clarify its epidemiological and clinical impact.

Original language	English
Pages (from-to)	2428-2430
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	55
Issue number	5
DOIs	https://doi.org/10.1128/AAC.01208-10
State	Published - May 2011
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1128/AAC.01208-10

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Montealegre, M. C., Correa, A., Briceño, D. F., Rosas, N. C., De La Cadena, E., Ruiz, S. J., Mojica, M. F., Camargo, R. D., Zuluaga, I., Marin, A., Quinn, J. P., Villegas, M. V., Mendoza, H., Cubides, F. A., Melendez, M. P., Quintero, L. A., Galeano, I. L., Porras, B., Ortiz, G., ... Gonzalez, L. (2011). Novel VIM metallo-β-lactamase variant, VIM-24, from a Klebsiella pneumoniae isolate from Colombia. Antimicrobial Agents and Chemotherapy, 55(5), 2428-2430. https://doi.org/10.1128/AAC.01208-10

@article{e4c54e78ed274ed3b34455e97715ee4c,

title = "Novel VIM metallo-β-lactamase variant, VIM-24, from a Klebsiella pneumoniae isolate from Colombia",

abstract = "We report the emergence of a novel VIM variant (VIM-24) in a Klebsiella pneumoniae isolate in Colombia. The isolate displays MICs for carbapenems below the resistance breakpoints, posing a real challenge for its detection. The blaVIM-24 gene was located within a class 1 integron carried on a large plasmid. Further studies are needed to clarify its epidemiological and clinical impact.",

author = "Montealegre, \{Maria Camila\} and Adriana Correa and Brice{\~n}o, \{David F.\} and Rosas, \{Natalia C.\} and \{De La Cadena\}, Elsa and Ruiz, \{Sory J.\} and Mojica, \{Maria F.\} and Camargo, \{Ruben Dario\} and Ivan Zuluaga and Adriana Marin and Quinn, \{John P.\} and Villegas, \{Maria Virginia\} and Henry Mendoza and Cubides, \{Flor Angela\} and Melendez, \{Martha Patricia\} and Quintero, \{Luz Angelica\} and Galeano, \{Ilba Liliana\} and Beatriz Porras and Guillermo Ortiz and Lopez, \{Luz Mila\} and Henry Oliveros and Gonzalez, \{Maria Nilse\} and Angela Pescador and Monica Ballesteros and Sandra Valderrama and Alirio Rodriguez and Jairo Perez and Gomez, \{Carlos Ignacio\} and Jaime Lopez and Jorge Donado and Monica Cuartas and Correa, \{Ana Lucia\} and Casta{\~n}eda, \{Lina Marcela\} and Julian Betancourth and Villa, \{Juan David\} and Jorge Nagles and Gonzalez, \{Nancy Estella\} and Magda Orjuela and Quiroga, \{Ana Cristina\} and Rodrigo Agudelo and Carolina Rios and Martha Vallejo and Melguizo, \{Luz Marina\} and Dora Rivas and Sergio Velez and Ernesto Martinez and O{\~n}ate, \{Jose Millan\} and Christian Pallares and Gallardo, \{Luz Marina\} and Bohorques, \{Alba Lucia\} and Nancy Villamarin and Fernando Rosso and Velez, \{Juan Diego\} and Jose Garcia and Monica Recalde and Alejandra Toala and Echeverry, \{John Jairo\} and Beatriz Lopez and Claudia Barcenas and Karol Monsalve and Villar, \{Luis Angel\} and Mayerly Anaya and Agustin Vega and Amaya, \{Miriam Fanny\} and Matha Jacome and Rocio Abaunza and Martin Mej{\'i}a and Angela Mendoza and Llano, \{Carmen Elisa\} and Myriam Gomez and Rodolfo Cabrales and Amparo Ovalle and Claudia Echeverry and Aldana, \{M. Del Rosario\} and Pablo Lopez and Luis Gonzalez",

year = "2011",

month = may,

doi = "10.1128/AAC.01208-10",

language = "English",

volume = "55",

pages = "2428--2430",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "5",

}

Montealegre, MC, Correa, A, Briceño, DF, Rosas, NC, De La Cadena, E, Ruiz, SJ, Mojica, MF, Camargo, RD, Zuluaga, I, Marin, A, Quinn, JP, Villegas, MV, Mendoza, H, Cubides, FA, Melendez, MP, Quintero, LA, Galeano, IL, Porras, B, Ortiz, G, Lopez, LM, Oliveros, H, Gonzalez, MN, Pescador, A, Ballesteros, M, Valderrama, S, Rodriguez, A, Perez, J, Gomez, CI, Lopez, J, Donado, J, Cuartas, M, Correa, AL, Castañeda, LM, Betancourth, J, Villa, JD, Nagles, J, Gonzalez, NE, Orjuela, M, Quiroga, AC, Agudelo, R, Rios, C, Vallejo, M, Melguizo, LM, Rivas, D, Velez, S, Martinez, E, Oñate, JM, Pallares, C, Gallardo, LM, Bohorques, AL, Villamarin, N, Rosso, F, Velez, JD, Garcia, J, Recalde, M, Toala, A, Echeverry, JJ, Lopez, B, Barcenas, C, Monsalve, K, Villar, LA, Anaya, M, Vega, A, Amaya, MF, Jacome, M, Abaunza, R, Mejía, M, Mendoza, A, Llano, CE, Gomez, M, Cabrales, R, Ovalle, A, Echeverry, C, Aldana, MDR, Lopez, P & Gonzalez, L 2011, 'Novel VIM metallo-β-lactamase variant, VIM-24, from a Klebsiella pneumoniae isolate from Colombia', Antimicrobial Agents and Chemotherapy, vol. 55, no. 5, pp. 2428-2430. https://doi.org/10.1128/AAC.01208-10

TY - JOUR

T1 - Novel VIM metallo-β-lactamase variant, VIM-24, from a Klebsiella pneumoniae isolate from Colombia

AU - Montealegre, Maria Camila

AU - Correa, Adriana

AU - Briceño, David F.

AU - Rosas, Natalia C.

AU - De La Cadena, Elsa

AU - Ruiz, Sory J.

AU - Mojica, Maria F.

AU - Camargo, Ruben Dario

AU - Zuluaga, Ivan

AU - Marin, Adriana

AU - Quinn, John P.

AU - Villegas, Maria Virginia

AU - Mendoza, Henry

AU - Cubides, Flor Angela

AU - Melendez, Martha Patricia

AU - Quintero, Luz Angelica

AU - Galeano, Ilba Liliana

AU - Porras, Beatriz

AU - Ortiz, Guillermo

AU - Lopez, Luz Mila

AU - Oliveros, Henry

AU - Gonzalez, Maria Nilse

AU - Pescador, Angela

AU - Ballesteros, Monica

AU - Valderrama, Sandra

AU - Rodriguez, Alirio

AU - Perez, Jairo

AU - Gomez, Carlos Ignacio

AU - Lopez, Jaime

AU - Donado, Jorge

AU - Cuartas, Monica

AU - Correa, Ana Lucia

AU - Castañeda, Lina Marcela

AU - Betancourth, Julian

AU - Villa, Juan David

AU - Nagles, Jorge

AU - Gonzalez, Nancy Estella

AU - Orjuela, Magda

AU - Quiroga, Ana Cristina

AU - Agudelo, Rodrigo

AU - Rios, Carolina

AU - Vallejo, Martha

AU - Melguizo, Luz Marina

AU - Rivas, Dora

AU - Velez, Sergio

AU - Martinez, Ernesto

AU - Oñate, Jose Millan

AU - Pallares, Christian

AU - Gallardo, Luz Marina

AU - Bohorques, Alba Lucia

AU - Villamarin, Nancy

AU - Rosso, Fernando

AU - Velez, Juan Diego

AU - Garcia, Jose

AU - Recalde, Monica

AU - Toala, Alejandra

AU - Echeverry, John Jairo

AU - Lopez, Beatriz

AU - Barcenas, Claudia

AU - Monsalve, Karol

AU - Villar, Luis Angel

AU - Anaya, Mayerly

AU - Vega, Agustin

AU - Amaya, Miriam Fanny

AU - Jacome, Matha

AU - Abaunza, Rocio

AU - Mejía, Martin

AU - Mendoza, Angela

AU - Llano, Carmen Elisa

AU - Gomez, Myriam

AU - Cabrales, Rodolfo

AU - Ovalle, Amparo

AU - Echeverry, Claudia

AU - Aldana, M. Del Rosario

AU - Lopez, Pablo

AU - Gonzalez, Luis

PY - 2011/5

Y1 - 2011/5

N2 - We report the emergence of a novel VIM variant (VIM-24) in a Klebsiella pneumoniae isolate in Colombia. The isolate displays MICs for carbapenems below the resistance breakpoints, posing a real challenge for its detection. The blaVIM-24 gene was located within a class 1 integron carried on a large plasmid. Further studies are needed to clarify its epidemiological and clinical impact.

AB - We report the emergence of a novel VIM variant (VIM-24) in a Klebsiella pneumoniae isolate in Colombia. The isolate displays MICs for carbapenems below the resistance breakpoints, posing a real challenge for its detection. The blaVIM-24 gene was located within a class 1 integron carried on a large plasmid. Further studies are needed to clarify its epidemiological and clinical impact.

UR - https://www.scopus.com/pages/publications/79955536125

U2 - 10.1128/AAC.01208-10

DO - 10.1128/AAC.01208-10

M3 - Article

C2 - 21282438

AN - SCOPUS:79955536125

SN - 0066-4804

VL - 55

SP - 2428

EP - 2430

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 5

ER -

Novel VIM metallo-β-lactamase variant, VIM-24, from a Klebsiella pneumoniae isolate from Colombia

Abstract

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