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Musculoskeletal infection in orthopaedic trauma: Assessment of the 2018 international consensus meeting on musculoskeletal infection

  • ICM Orthopaedic Trauma Work Group
  • Vanderbilt University Medical Center
  • University Hospitals Leuven
  • Tenet Healthcare Corporation
  • Royal Brisbane and Women's Hospital
  • Orthopaedic Research Centre of Australia
  • Macquarie University
  • New York University
  • Virginia Commonwealth University
  • Oxford University Hospitals NHS Foundation Trust
  • Royal College of Surgeons in Ireland
  • Hospital Universitario San Ignacio
  • Keck School of Medicine of USC
  • Stellenbosch University
  • Boston University
  • University Hospital Mannheim
  • University of Maryland, Baltimore
  • Universidade Federal de São Paulo
  • Massachusetts General Hospital
  • University Hospital Basel
  • Thomas Jefferson University Hospital
  • University of Washington
  • University of Thessaly
  • University of Leeds
  • John Peter Smith Hospital Fort Worth
  • Clínica Universitaria Colombia
  • Orthopaedic Associates of Wisconsin
  • Fundación Santa Fe de Bogotá
  • Helios ENDO-Klinik Hamburg
  • Ludwig Maximilian University of Munich
  • Complutense University
  • University of KwaZulu-Natal
  • AMEOS Klinikum Seepark Geestland
  • Limassol General Hospital
  • Indiana University Bloomington
  • Hamad Medical Corporation
  • University of Miami Leonard M. Miller School of Medicine
  • Sinai Hospital of Baltimore
  • Fundación Hospital Pediátrico la Misericordia
  • Lund University
  • University of Memphis
  • Jefferson Health
  • Universidad de los Andes Colombia
  • Stanford University School of Medicine
  • Thomas Jefferson University
  • Duke University
  • University of Cincinnati
  • Royal Darwin Hospital
  • Pelvis Center
  • Harvard University
  • St. Marianna University School of Medicine
  • Vilnius University
  • Universidad Javeriana
  • University of Minnesota Twin Cities
  • Maghreb Medical
  • Hospital Salud Integral
  • University Hospital Regensburg
  • University of Maryland Medical System
  • University of Arizona

Research output: Contribution to journalArticlepeer-review

65 Scopus citations

Abstract

Fracture-related infections (FRIs) are among the most common complications following fracture fixation, and they have a huge economic and functional impact on patients. Because consensus guidelines with respect to prevention, diagnosis, and treatment of this major complication are scarce, delegates from different countries gathered in Philadelphia in July 2018 as part of the Second International Consensus Meeting (ICM) on Musculoskeletal Infection. This paper summarizes the discussion and recommendations from that consensus meeting, using the Delphi technique, with a focus on FRIs. A standardized definition that was based on diagnostic criteria was endorsed, which will hopefully improve reporting and research on FRIs in the future. Furthermore, this paper provides a grade of evidence (strong, moderate, limited, or consensus) for strategies and practices that prevent and treat infection. The grade of evidence is based on the quality of evidence as utilized by the American Academy of Orthopaedic Surgeons. The guidelines presented herein focus not only on the appropriate use of antibiotics, but also on practices for the timing of fracture fixation, soft-tissue coverage, and bone defect and hardware management. We hope that this summary as well as the full document by the International Consensus Group are utilized by those who are charged with musculoskeletal care internationally to optimize their management strategies for the prevention and treatment of FRIs.

Original languageEnglish
Pages (from-to)E441-E449
JournalJournal of Bone and Joint Surgery
Volume102
Issue number10
StatePublished - 20 May 2020

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