Abstract
Objective: To determine glucose behaviour using continuous glucose monitoring (CGM) in insulin-treated patients with type 2 diabetes on haemodialysis (HD) at San José Hospital - Fresenius Medical Care Renal Unit.
Materials and methods: Longitudinal descriptive study conducted between April and August 2016, including insulin- treated patients with type 2 diabetes and renal failure on haemodialysis. The variables measured included severe or asymptomatic hypoglicaemia, hyperglicaemia, blood sugar variability, demographic characteristics and paraclinical variables.
Results: Overall, 25 patients were included and 72% of them were males. Glycosylated haemoglobin (HbA1c) levels were 8.35% (± 2,34). CGM showed high variability, with the data showing a 67.7% trend towards hyperglicaemia, and alowering of tissue glucose during HD. There were 52 hypoglycaemic episodes detected, with a higher frequency during the days without dialysis and during the day. There was a lower ratio of hypoglicaemic episodes with the use of insulin Glargine.
Conclusions: CGM in diabetic patients on HD detected high blood sugar variability, hyperglycaemia predominantly during non-dialysis days, and a higher number of hypoglycaemic episodes when compared with blood glucose measurements.
Materials and methods: Longitudinal descriptive study conducted between April and August 2016, including insulin- treated patients with type 2 diabetes and renal failure on haemodialysis. The variables measured included severe or asymptomatic hypoglicaemia, hyperglicaemia, blood sugar variability, demographic characteristics and paraclinical variables.
Results: Overall, 25 patients were included and 72% of them were males. Glycosylated haemoglobin (HbA1c) levels were 8.35% (± 2,34). CGM showed high variability, with the data showing a 67.7% trend towards hyperglicaemia, and alowering of tissue glucose during HD. There were 52 hypoglycaemic episodes detected, with a higher frequency during the days without dialysis and during the day. There was a lower ratio of hypoglicaemic episodes with the use of insulin Glargine.
Conclusions: CGM in diabetic patients on HD detected high blood sugar variability, hyperglycaemia predominantly during non-dialysis days, and a higher number of hypoglycaemic episodes when compared with blood glucose measurements.
| Translated title of the contribution | Continuous glucose monitoring over a 6-day period in insulin-treated patients with type 2 diabetes on haemodialysis at San José Hospital, Bogotá |
|---|---|
| Original language | Spanish |
| Pages (from-to) | 13-20 |
| Journal | Revista Colombiana de Endocrinología, Diabetes & Metabolismo |
| Volume | 5 |
| Issue number | 4 |
| DOIs | |
| State | Published - 20 Nov 2018 |
Keywords
- Diabetes mellitus
- chronic renal failure
- glucose
- monitoring
- dialysis
