Leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus

Diana Nathalie Rincón-Riaño; Daniel G. Fernández-Ávila; Juan M. Gutiérrez

doi:10.1016/j.rcreu.2017.05.003

Leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus

Diana Nathalie Rincón-Riaño, Daniel G. Fernández-Ávila, Juan M. Gutiérrez

Hospital Universitario San Ignacio

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Leflunomide is an immunomodulatory agent widely used in rheumatoid arthritis and other rheumatic diseases like psoriatic arthritis and systemic lupus erythematosus. Although its safety profile is generally good, side effects have been reported in up to 20% of cases. Severe reactions, such as toxic epidermal necrolysis and Stevens Johnson syndrome are rare. The case is presented of a leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus.

Translated title of the contribution	Síndrome de Stevens Johnson inducido por leflunomida en un paciente con lupus eritematoso sistémico
Original language	English
Pages (from-to)	242-246
Number of pages	5
Journal	Revista Colombiana de Reumatologia
Volume	24
Issue number	4
DOIs	https://doi.org/10.1016/j.rcreu.2017.05.003
State	Published - Oct 2017
Externally published	Yes

Keywords

Adverse effects
Leflunomide
Stevens-Johnson syndrome

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title = "Leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus",

abstract = "Leflunomide is an immunomodulatory agent widely used in rheumatoid arthritis and other rheumatic diseases like psoriatic arthritis and systemic lupus erythematosus. Although its safety profile is generally good, side effects have been reported in up to 20% of cases. Severe reactions, such as toxic epidermal necrolysis and Stevens Johnson syndrome are rare. The case is presented of a leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus.",

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author = "Rinc{\'o}n-Ria{\~n}o, {Diana Nathalie} and Fern{\'a}ndez-{\'A}vila, {Daniel G.} and Guti{\'e}rrez, {Juan M.}",

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AU - Rincón-Riaño, Diana Nathalie

AU - Fernández-Ávila, Daniel G.

AU - Gutiérrez, Juan M.

PY - 2017/10

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N2 - Leflunomide is an immunomodulatory agent widely used in rheumatoid arthritis and other rheumatic diseases like psoriatic arthritis and systemic lupus erythematosus. Although its safety profile is generally good, side effects have been reported in up to 20% of cases. Severe reactions, such as toxic epidermal necrolysis and Stevens Johnson syndrome are rare. The case is presented of a leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus.

AB - Leflunomide is an immunomodulatory agent widely used in rheumatoid arthritis and other rheumatic diseases like psoriatic arthritis and systemic lupus erythematosus. Although its safety profile is generally good, side effects have been reported in up to 20% of cases. Severe reactions, such as toxic epidermal necrolysis and Stevens Johnson syndrome are rare. The case is presented of a leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus.

KW - Adverse effects

KW - Leflunomide

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JO - Revista Colombiana de Reumatologia

JF - Revista Colombiana de Reumatologia

IS - 4

ER -

Leflunomide-induced Stevens Johnson syndrome in a patient with systemic lupus erythematosus

Abstract

Keywords

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