Abstract
Longipilin acetate is the compound exhibiting cytotoxicity, isolated from endemic plant specie from Colombia, South America, Espeletia killipii Cuatr. Longipilin acetate is a sesquiterpenelactone having the ability to induce apoptosis in several breast cancer cell-lines like MCF-7 y CSC-1595 (obtained from National Cancer Institute, Bogotá Colombia), Morphological examination, nuclear DNA fragmentation, tunel and flow cytometry were used to evaluate apoptosis. Therefore longipilin acetate is a compound showing potential as an antitumor agent.
| Translated title of the contribution | "Induction of apoptosis by the citotoxic active principle of Espeletia killipii Cuatr. on human cell lines" |
|---|---|
| Original language | Portuguese |
| Pages (from-to) | 497-500 |
| Number of pages | 4 |
| Journal | Revista Brasileira de Farmacognosia |
| Volume | 17 |
| Issue number | 4 |
| DOIs | |
| State | Published - 2007 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Apoptosis activity
- Asteraceae
- Espeletia killipii
- Sesquiterpenlactone
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