Inclusion body myositis: A differential diagnosis to consider in patients with myopathy refractory to immunosuppressants. Two case reports

Fernando Bolaños-Toro, Daniel Arias-Jaramillo, Manuela Aun-Mejía, Juliana Castro-Henao, Daniel G. Fernández-Ávila, Lina María Saldarriaga-Rivera

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1 Scopus citations

Abstract

Inclusion body myositis is part of the group of inflammatory myopathies, representing 30% of this group of diseases, and is considered an orphan disease because its estimated prevalence is less than 5 per 10,000 inhabitants. It produces weakness and atrophy of the proximal and distal muscles. The pathophysiological mechanisms are mainly autoimmune, inflammatory, and degenerative. The cases are presented on 2 female patients who came to the emergency department due to progressive loss of upper and lower limb strength, and progressive asymmetric muscle weakness.

Translated title of the contributionMiopatía por cuerpos de inclusión: un diagnóstico diferencial que considerar en pacientes con miopatía refractaria a inmunosupresores. Reporte de 2 casos
Original languageEnglish
Pages (from-to)300-305
Number of pages6
JournalRevista Colombiana de Reumatologia
Volume28
Issue number4
DOIs
StatePublished - 01 Oct 2021
Externally publishedYes

Keywords

  • Biopsy
  • Electromyography
  • Inclusion bodies
  • Muscular weakness
  • Myositis

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