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Immune system activation by natural products and complex fractions: A network pharmacology approach in cancer treatment

  • University of Geneva
  • University of Lausanne
  • Universidad Javeriana

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

Natural products and traditional herbal medicine are an important source of alternative bioactive compounds but very few plant-based preparations have been scientifically evaluated and validated for their potential as medical treatments. However, a promising field in the current therapies based on plant-derived compounds is the study of their immunomodulation properties and their capacity to activate the immune system to fight against multifactorial diseases like cancer. In this review we discuss how network pharmacology could help to characterize and validate natural single molecules or more complex preparations as promising cancer therapies based on their multitarget capacities.

Original languageEnglish
Pages (from-to)154-166
Number of pages13
JournalCell Stress
Volume4
Issue number7
DOIs
StatePublished - Jul 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Cancer
  • Herbal medicine
  • Immune response
  • Immunogenic cell death
  • Immunomodulation
  • Natural products
  • Network pharmacology

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