Herpes simplex virus type 2 meningitis as a manifestation of Good’s syndrome

Lorena Matta; María Camila Ramírez-Velasco; Andrés Felipe Zea-Vera

doi:10.1007/s13365-019-00819-x

Herpes simplex virus type 2 meningitis as a manifestation of Good’s syndrome

Lorena Matta, María Camila Ramírez-Velasco, Andrés Felipe Zea-Vera

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Good’s syndrome is a primary immunodeficiency phenocopy characterized for thymoma and immunodeficiency. The most frequent clinical presentation is recurrent or opportunistic infections, hematological alterations, and chronic diarrhea. We treated a 66-year-old man who consulted for 5 days of headache and diplopia with right sixth cranial nerve palsy at examination. Patient reported chronic diarrhea and prolonged febrile syndrome accompanied by weight loss of 23 kg in the last year. Exhaustive evaluation revealed Herpes simplex virus (HSV) type 2 meningitis, eosinophilic colitis, and type A thymoma. Severe antibody deficiency (hypogammaglobulinemia) associated with thymoma confirmed the diagnosis of Good’s syndrome.

Original language	English
Pages (from-to)	429-432
Number of pages	4
Journal	Journal of NeuroVirology
Volume	26
Issue number	3
DOIs	https://doi.org/10.1007/s13365-019-00819-x
State	Published - 01 Jun 2020
Externally published	Yes

Keywords

Good’s syndrome
Herpes simplex virus type (HSV) 2
Hypogammaglobulinemia
Mollaret meningitis
Primary immunodeficiency
Thymoma

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/s13365-019-00819-x

Cite this

@article{65cabf097e2f47cf9c00b84a70d5a7fa,

title = "Herpes simplex virus type 2 meningitis as a manifestation of Good{\textquoteright}s syndrome",

abstract = "Good{\textquoteright}s syndrome is a primary immunodeficiency phenocopy characterized for thymoma and immunodeficiency. The most frequent clinical presentation is recurrent or opportunistic infections, hematological alterations, and chronic diarrhea. We treated a 66-year-old man who consulted for 5 days of headache and diplopia with right sixth cranial nerve palsy at examination. Patient reported chronic diarrhea and prolonged febrile syndrome accompanied by weight loss of 23 kg in the last year. Exhaustive evaluation revealed Herpes simplex virus (HSV) type 2 meningitis, eosinophilic colitis, and type A thymoma. Severe antibody deficiency (hypogammaglobulinemia) associated with thymoma confirmed the diagnosis of Good{\textquoteright}s syndrome.",

keywords = "Good{\textquoteright}s syndrome, Herpes simplex virus type (HSV) 2, Hypogammaglobulinemia, Mollaret meningitis, Primary immunodeficiency, Thymoma",

author = "Lorena Matta and Ram{\'i}rez-Velasco, {Mar{\'i}a Camila} and Zea-Vera, {Andr{\'e}s Felipe}",

note = "Publisher Copyright: {\textcopyright} 2019, Journal of NeuroVirology, Inc.",

year = "2020",

month = jun,

day = "1",

doi = "10.1007/s13365-019-00819-x",

language = "English",

volume = "26",

pages = "429--432",

journal = "Journal of NeuroVirology",

issn = "1355-0284",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "3",

}

TY - JOUR

T1 - Herpes simplex virus type 2 meningitis as a manifestation of Good’s syndrome

AU - Matta, Lorena

AU - Ramírez-Velasco, María Camila

AU - Zea-Vera, Andrés Felipe

PY - 2020/6/1

Y1 - 2020/6/1

N2 - Good’s syndrome is a primary immunodeficiency phenocopy characterized for thymoma and immunodeficiency. The most frequent clinical presentation is recurrent or opportunistic infections, hematological alterations, and chronic diarrhea. We treated a 66-year-old man who consulted for 5 days of headache and diplopia with right sixth cranial nerve palsy at examination. Patient reported chronic diarrhea and prolonged febrile syndrome accompanied by weight loss of 23 kg in the last year. Exhaustive evaluation revealed Herpes simplex virus (HSV) type 2 meningitis, eosinophilic colitis, and type A thymoma. Severe antibody deficiency (hypogammaglobulinemia) associated with thymoma confirmed the diagnosis of Good’s syndrome.

AB - Good’s syndrome is a primary immunodeficiency phenocopy characterized for thymoma and immunodeficiency. The most frequent clinical presentation is recurrent or opportunistic infections, hematological alterations, and chronic diarrhea. We treated a 66-year-old man who consulted for 5 days of headache and diplopia with right sixth cranial nerve palsy at examination. Patient reported chronic diarrhea and prolonged febrile syndrome accompanied by weight loss of 23 kg in the last year. Exhaustive evaluation revealed Herpes simplex virus (HSV) type 2 meningitis, eosinophilic colitis, and type A thymoma. Severe antibody deficiency (hypogammaglobulinemia) associated with thymoma confirmed the diagnosis of Good’s syndrome.

KW - Good’s syndrome

KW - Herpes simplex virus type (HSV) 2

KW - Hypogammaglobulinemia

KW - Mollaret meningitis

KW - Primary immunodeficiency

KW - Thymoma

UR - http://www.scopus.com/inward/record.url?scp=85076793348&partnerID=8YFLogxK

U2 - 10.1007/s13365-019-00819-x

DO - 10.1007/s13365-019-00819-x

M3 - Article

C2 - 31858482

AN - SCOPUS:85076793348

SN - 1355-0284

VL - 26

SP - 429

EP - 432

JO - Journal of NeuroVirology

JF - Journal of NeuroVirology

IS - 3

ER -

Herpes simplex virus type 2 meningitis as a manifestation of Good’s syndrome

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this