TY - GEN
T1 - Fast-marching contours for the segmentation of vessel lumen in CTA cross-sections
AU - Milwer, Michael Baltaxe
AU - Valencia, Leonardo Flórez
AU - Hoyos, Marcela Hernández
AU - Magnin, Isabelle E.
AU - Orkisz, Maciej
PY - 2007
Y1 - 2007
N2 - This work deals with the segmentation of the arterial lumen in cross-sections of CT angiography (CTA) images, by means of active contours. Within the context of the fast-marching method, a new speed-control function is proposed in order to cope with strongly variable contrasts along the perimeter of the contour. This function was devised to guarantee the existence of a time T at which the fast-marching front fits the actual boundary of the vessel lumen, despite calcifications and other neighboring structures. Instead of using the magnitude of the image intensity gradient alone, this function includes exponential factors that strongly decrease the propagation speed when the front moves beyond the local maxima of the gradient magnitude and beyond the range of luminal intensities in CTA images. The propagation is stopped when the the growth of the area A encompassed by the front becomes very slow, which is characterized by a large value of dT/dA. The segmentation was evaluated in 65 cross-sections of carotid arteries from 13 different patients, by comparison with contours traced by a radiologist. The mean sensitivity was 0.849 and the mean positive predictive value was 0.797.
AB - This work deals with the segmentation of the arterial lumen in cross-sections of CT angiography (CTA) images, by means of active contours. Within the context of the fast-marching method, a new speed-control function is proposed in order to cope with strongly variable contrasts along the perimeter of the contour. This function was devised to guarantee the existence of a time T at which the fast-marching front fits the actual boundary of the vessel lumen, despite calcifications and other neighboring structures. Instead of using the magnitude of the image intensity gradient alone, this function includes exponential factors that strongly decrease the propagation speed when the front moves beyond the local maxima of the gradient magnitude and beyond the range of luminal intensities in CTA images. The propagation is stopped when the the growth of the area A encompassed by the front becomes very slow, which is characterized by a large value of dT/dA. The segmentation was evaluated in 65 cross-sections of carotid arteries from 13 different patients, by comparison with contours traced by a radiologist. The mean sensitivity was 0.849 and the mean positive predictive value was 0.797.
UR - http://www.scopus.com/inward/record.url?scp=57649234967&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2007.4352409
DO - 10.1109/IEMBS.2007.4352409
M3 - Conference contribution
C2 - 18002075
AN - SCOPUS:57649234967
SN - 1424407885
SN - 9781424407880
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 791
EP - 794
BT - 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Y2 - 23 August 2007 through 26 August 2007
ER -