TY - JOUR
T1 - Enfermedad relacionada con los implantes mamarios de silicona o síndrome de ASIA relacionado con los implantes mamarios: consenso de expertos
T2 - consenso de expertos
AU - Hormaza-Jaramillo, Andrés A.
AU - Romero Chamorro, Damaris
AU - Santamaría Alza, Yeison
AU - Duque Restrepo, Alejandro
AU - Guarín Sastre, David Enrique
AU - Pachón Suárez, Jaime Eduardo
AU - Cadena Ríos, María Isabel
AU - Gil Calderón, Diana Rocío
AU - Fernández-Ávila, Daniel G.
AU - Mesa Betancur, Felipe
AU - Vásquez D., Gloria María
AU - Barbosa Landínez, Héctor Ernesto
AU - Rojas-Villarraga, Adriana
N1 - Publisher Copyright:
© 2025 Asociación Colombiana de Reumatología
PY - 2025
Y1 - 2025
N2 - AbstractIntroductionBreast augmentation surgeries are very common, but in recent years there has been a growing interest in their possible relationship with the appearance of nonspecific symptoms and signs, as well as the development of autoimmune disorders. The lack of a consensus about the syndrome is a controversial issue for the scientific community and generates uncertainty among women with breast implants in Colombia.ObjectiveTo provide guidelines for the evaluation, approach, and follow-up of silicone breast implant-related disease, or ASIA syndrome, based on evidence and clinical expert opinion.MethodsExperts from the Colombian Society of Rheumatology and the Colombian Society of Plastic Surgery and an independent methodological team developed a systematic literature review and consensus using a modified Delphi method.ResultsThe evidence for an association between silicone breast implants and the development of symptoms, autoimmune or rheumatic diseases is limited, and a definitive causal relationship has not been demonstrated. The low certainty of the evidence is due to bias, study heterogeneity, and non-specific, self-reported symptoms. On this basis, 22 consensus statements were formulated, highlighting the importance of an individualized medical approach, comprehensive evaluation, and effective communication with patients about risks and expectations before implantation and explantation procedures.ConclusionsEvaluation and therapeutic decisions in women with suspected silicone implant-associated disease should be based on available scientific evidence. Future research should explore the causality of the syndrome and improve disease characterization.
AB - AbstractIntroductionBreast augmentation surgeries are very common, but in recent years there has been a growing interest in their possible relationship with the appearance of nonspecific symptoms and signs, as well as the development of autoimmune disorders. The lack of a consensus about the syndrome is a controversial issue for the scientific community and generates uncertainty among women with breast implants in Colombia.ObjectiveTo provide guidelines for the evaluation, approach, and follow-up of silicone breast implant-related disease, or ASIA syndrome, based on evidence and clinical expert opinion.MethodsExperts from the Colombian Society of Rheumatology and the Colombian Society of Plastic Surgery and an independent methodological team developed a systematic literature review and consensus using a modified Delphi method.ResultsThe evidence for an association between silicone breast implants and the development of symptoms, autoimmune or rheumatic diseases is limited, and a definitive causal relationship has not been demonstrated. The low certainty of the evidence is due to bias, study heterogeneity, and non-specific, self-reported symptoms. On this basis, 22 consensus statements were formulated, highlighting the importance of an individualized medical approach, comprehensive evaluation, and effective communication with patients about risks and expectations before implantation and explantation procedures.ConclusionsEvaluation and therapeutic decisions in women with suspected silicone implant-associated disease should be based on available scientific evidence. Future research should explore the causality of the syndrome and improve disease characterization.
KW - ASIA syndrome
KW - Adjuvants immunologic
KW - Adyuvantes inmunológicos
KW - Breast implants
KW - Implantes mamarios
KW - Siliconas
KW - Silicones
KW - Síndrome ASIA
UR - https://www.scopus.com/pages/publications/105010210423
U2 - 10.1016/j.rcreu.2025.04.004
DO - 10.1016/j.rcreu.2025.04.004
M3 - Comentario/Debate
AN - SCOPUS:105010210423
SN - 0121-8123
VL - 33
JO - Revista Colombiana de Reumatologia
JF - Revista Colombiana de Reumatologia
IS - 1
M1 - 102186
ER -