Different Clinical Severity and Outcomes in a Cohort of Patients With Dengue With Warning Signs in an Endemic Latin American City

Mara Gómez-Zambrano; Daniela Torres-Hernández; Monica A. Murillo-Ortiz; Isabel C. Hurtado; Diana M. Dávalos; Erika Cantor; Pio López; Nathan D. Grubaugh; Eduardo López-Medina

doi:10.1093/ofid/ofaf227

Different Clinical Severity and Outcomes in a Cohort of Patients With Dengue With Warning Signs in an Endemic Latin American City

Mara Gómez-Zambrano
, Daniela Torres-Hernández
, Monica A. Murillo-Ortiz
, Isabel C. Hurtado
, Diana M. Dávalos
, Erika Cantor
, Pio López
, Nathan D. Grubaugh
, Eduardo López-Medina

Department of Clinical Epidemiology and Biostatistics

Universidad del Valle
State Department of Public Health
Centro de Estudios en Infectología Pediátrica CEIP
Yale University
KU Leuven
Clínica Imbanaco - Quiron Salud

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

We used a detailed dengue classification to assess the variability in disease severity and outcomes in a cohort of patients classified as “dengue with warning signs” according to the 2009 World Health Organization (WHO) criteria. We describe a wide range of severity and outcomes, which highlights the need and potential to improve the current WHO dengue classification.

Original language	English
Article number	ofaf227
Journal	Open Forum Infectious Diseases
Volume	12
Issue number	4
DOIs	https://doi.org/10.1093/ofid/ofaf227
State	Published - 01 Apr 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

classification
dengue
outcomes
severity
warning signs

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10.1093/ofid/ofaf227

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Gómez-Zambrano, M., Torres-Hernández, D., Murillo-Ortiz, M. A., Hurtado, I. C., Dávalos, D. M., Cantor, E., López, P., Grubaugh, N. D., & López-Medina, E. (2025). Different Clinical Severity and Outcomes in a Cohort of Patients With Dengue With Warning Signs in an Endemic Latin American City. Open Forum Infectious Diseases, 12(4), Article ofaf227. https://doi.org/10.1093/ofid/ofaf227

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abstract = "We used a detailed dengue classification to assess the variability in disease severity and outcomes in a cohort of patients classified as “dengue with warning signs” according to the 2009 World Health Organization (WHO) criteria. We describe a wide range of severity and outcomes, which highlights the need and potential to improve the current WHO dengue classification.",

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Gómez-Zambrano, M, Torres-Hernández, D, Murillo-Ortiz, MA, Hurtado, IC, Dávalos, DM, Cantor, E, López, P, Grubaugh, ND & López-Medina, E 2025, 'Different Clinical Severity and Outcomes in a Cohort of Patients With Dengue With Warning Signs in an Endemic Latin American City', Open Forum Infectious Diseases, vol. 12, no. 4, ofaf227. https://doi.org/10.1093/ofid/ofaf227

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AU - Gómez-Zambrano, Mara

AU - Torres-Hernández, Daniela

AU - Murillo-Ortiz, Monica A.

AU - Hurtado, Isabel C.

AU - Dávalos, Diana M.

AU - Cantor, Erika

AU - López, Pio

AU - Grubaugh, Nathan D.

AU - López-Medina, Eduardo

PY - 2025/4/1

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AB - We used a detailed dengue classification to assess the variability in disease severity and outcomes in a cohort of patients classified as “dengue with warning signs” according to the 2009 World Health Organization (WHO) criteria. We describe a wide range of severity and outcomes, which highlights the need and potential to improve the current WHO dengue classification.

KW - classification

KW - dengue

KW - outcomes

KW - severity

KW - warning signs

UR - https://www.scopus.com/pages/publications/105003677475

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DO - 10.1093/ofid/ofaf227

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ER -

Different Clinical Severity and Outcomes in a Cohort of Patients With Dengue With Warning Signs in an Endemic Latin American City

Abstract

UN SDGs

Keywords

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