Desenlaces tempranos del manejo de la asfixia perinatal con Cool-Cap® y manta

Introduction: Short-term results obtained with body cooling using Cool-Cap®️ and blanket are controversial. The outcomes of the two intervention modalities are presented under the same protocol and institution. Patients and methods: ambidirectional cohort study of newborns with moderate or severe perinatal asphyxia treated with controlled hypothermia between 2018 and 2020 in a hospital in Bogotá, Colombia. Results: 164 patients received therapeutic hypothermia with the mentioned devices (Cool-Cap®️: 54.2%; Manta: 45.7%). Mortality was 11.2% and 16% respectively, with a higher proportion of patients with Sarnat III in the latter group (16% vs. 6%). The Cool-Cap®️ group presented more cardiovascular disorders (60%); pulmonary hypertension and hematological disorders had a similar proportion in both groups. In both interventions, more than half of the patients were admitted outside therapeutic window period and had an overall mortality of 14.8% (Cool-Cap®️ n=7 and blanket n=7). Conclusions: overall mortality was 13.4%, lower than the one reported in literature, which varies between 14% and 20%, despite the fact that more than half of the patients were admitted outside the therapeutic window period. This being greater in the blanket group, a difference that is explained by the disparity in the distribution of the prognostic factors at admission of both groups.