Confirmed SARS-CoV-2 infection and mortality: Associated factors in hospitalized people 75 and older

Samir Alejandro Aruachan-Torres; Diego Andrés Chavarro-Carvajal; Carlos José Ariza-Galindo; Ronald Camilo Gómez Arteaga; Sandra Milena Caicedo-Correa; Carlos Alberto Cano Gutierrez

doi:10.29333/ejgm/13042

Confirmed SARS-CoV-2 infection and mortality: Associated factors in hospitalized people 75 and older

Samir Alejandro Aruachan-Torres, Diego Andrés Chavarro-Carvajal, Carlos José Ariza-Galindo, Ronald Camilo Gómez Arteaga, Sandra Milena Caicedo-Correa, Carlos Alberto Cano Gutierrez

Research output: Contribution to journal › Article › peer-review

Abstract

Introduction: COVID-19 infection in the elderly posed challenges in health systems and clinical care by health personnel. Objective: To describe the factors associated with mortality in persons aged 75 and older with COVID-19 in a high complexity hospital in Bogotá, Colombia. Methods: Observational, analytical and retrospective study, including 509 patients aged 75 and older hospitalized with COVID-19. Results: 40.47% died during hospital stay. It was found that a shorter time of symptom onset at admission, a respiratory rate greater than 20 breaths per minute, having thrombocytopenia, elevated lactate dehydrogenase and elevated D-dimer were associated with higher in-hospital mortality. Conclusions: There is an association between mortality and the presence of dyspnea, fever and delirium. Paraclinical results with lactate dehydrogenase >350 (U/L), the presence of elevated D-dimer greater than 1,000 μg/L, as well as a Pa02/Fi02 ratio with a median of less than 90, were associated with higher mortality.

Translated title of the contribution	Mortalidad y factores asociados a infección confirmada por SARS-CoV2 en personas de 75 o más años hospitalizadas.
Original language	English
Article number	em479
Pages (from-to)	7
Journal	Electronic Journal of General Medicine
Volume	20
Issue number	3
DOIs	https://doi.org/10.29333/ejgm/13042
State	Published - Jun 2023
Event	22ND World Congress of Gerontology and Geriatrics IAGG 2022: IAGG 2022 - Plataforma virtual, gestionado desde Buenos Aires, Argentina, Buenos Aires, Argentina Duration: 16 Jun 2022 → 18 Jun 2022 https://iagg2022.org/en/home-site/

Keywords

Coronavirus infections
SARS-CoV-2
elderly
mortality

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10.29333/ejgm/13042

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title = "Confirmed SARS-CoV-2 infection and mortality: Associated factors in hospitalized people 75 and older",

abstract = "Introduction: COVID-19 infection in the elderly posed challenges in health systems and clinical care by health personnel. Objective: To describe the factors associated with mortality in persons aged 75 and older with COVID-19 in a high complexity hospital in Bogot{\'a}, Colombia. Methods: Observational, analytical and retrospective study, including 509 patients aged 75 and older hospitalized with COVID-19. Results: 40.47% died during hospital stay. It was found that a shorter time of symptom onset at admission, a respiratory rate greater than 20 breaths per minute, having thrombocytopenia, elevated lactate dehydrogenase and elevated D-dimer were associated with higher in-hospital mortality. Conclusions: There is an association between mortality and the presence of dyspnea, fever and delirium. Paraclinical results with lactate dehydrogenase >350 (U/L), the presence of elevated D-dimer greater than 1,000 μg/L, as well as a Pa02/Fi02 ratio with a median of less than 90, were associated with higher mortality.",

keywords = "Coronavirus infections, SARS-CoV-2, elderly, mortality, Coronavirus infections, SARS CoV-2, Elderly, mortality",

author = "Aruachan-Torres, {Samir Alejandro} and Chavarro-Carvajal, {Diego Andr{\'e}s} and Ariza-Galindo, {Carlos Jos{\'e}} and Arteaga, {Ronald Camilo G{\'o}mez} and Caicedo-Correa, {Sandra Milena} and {Cano Gutierrez}, {Carlos Alberto}",

note = "Publisher Copyright: {\textcopyright} 2023 by Author/s and Licensed by Modestum.; 22ND World Congress of Gerontology and Geriatrics IAGG 2022 ; Conference date: 16-06-2022 Through 18-06-2022",

year = "2023",

month = jun,

doi = "10.29333/ejgm/13042",

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AU - Chavarro-Carvajal, Diego Andrés

AU - Ariza-Galindo, Carlos José

AU - Arteaga, Ronald Camilo Gómez

AU - Caicedo-Correa, Sandra Milena

AU - Cano Gutierrez, Carlos Alberto

PY - 2023/6

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N2 - Introduction: COVID-19 infection in the elderly posed challenges in health systems and clinical care by health personnel. Objective: To describe the factors associated with mortality in persons aged 75 and older with COVID-19 in a high complexity hospital in Bogotá, Colombia. Methods: Observational, analytical and retrospective study, including 509 patients aged 75 and older hospitalized with COVID-19. Results: 40.47% died during hospital stay. It was found that a shorter time of symptom onset at admission, a respiratory rate greater than 20 breaths per minute, having thrombocytopenia, elevated lactate dehydrogenase and elevated D-dimer were associated with higher in-hospital mortality. Conclusions: There is an association between mortality and the presence of dyspnea, fever and delirium. Paraclinical results with lactate dehydrogenase >350 (U/L), the presence of elevated D-dimer greater than 1,000 μg/L, as well as a Pa02/Fi02 ratio with a median of less than 90, were associated with higher mortality.

AB - Introduction: COVID-19 infection in the elderly posed challenges in health systems and clinical care by health personnel. Objective: To describe the factors associated with mortality in persons aged 75 and older with COVID-19 in a high complexity hospital in Bogotá, Colombia. Methods: Observational, analytical and retrospective study, including 509 patients aged 75 and older hospitalized with COVID-19. Results: 40.47% died during hospital stay. It was found that a shorter time of symptom onset at admission, a respiratory rate greater than 20 breaths per minute, having thrombocytopenia, elevated lactate dehydrogenase and elevated D-dimer were associated with higher in-hospital mortality. Conclusions: There is an association between mortality and the presence of dyspnea, fever and delirium. Paraclinical results with lactate dehydrogenase >350 (U/L), the presence of elevated D-dimer greater than 1,000 μg/L, as well as a Pa02/Fi02 ratio with a median of less than 90, were associated with higher mortality.

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Confirmed SARS-CoV-2 infection and mortality: Associated factors in hospitalized people 75 and older

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