Comparative evaluation of immediate and residual antimicrobial effect of mouthwashes on biofilms associated with dental caries

Román Yesid Ramírez-Rueda, Dabeiba Adriana García-Robayo, Fredy Gamboa

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: Dental caries is associated to dysbiosis of dental biofilm. One of the most effective ways to prevent or control this disease is the use with mouthwashes. However, there is a great diversity of these products on the market, and there are few studies that determine their antimicrobial activity in biofilms. Aim: To evaluate antimicrobial activity of 4 commercial mouthrinses against 4 microorganisms in vitro biofilm model on HAp discs. Methods: The microorganisms included were S. mutans ATCC 35668, S. salivarius ATCC 13419, S. sanguinis ATCC 10556 and C. albicans ATCC 14053. Biofilms (in individual format and in binomial consortium) were developed on HAp discs for a period of 24 hours and they were subjected to two treatments with the four rinses, one with immediate effect (TEI- 5 minutes) and another residual (TER- 55 minutes). Results: The antimicrobial activity of all the mouthrinses was very similar. In mono and polymicrobial biofilms, TEI and TER were located, respectively, in inhibition ranges from 91.9 to 100%, and from 97 to 100%. Conclusion: All mouthwashes showed excellent antimicrobial activity on mounted biofilms, with inhibition values greater than 91.9% in the TEI treatment and 97% in the TER treatment. The best rinses were the identified as one and two, and the greatest action of these was on C. albicans.

Translated title of the contributionEvaluación comparativa del efecto antimicrobiano inmediato y residual de enjuagues bucales sobre biopelículas asociadas a caries dental
Original languageEnglish
Pages (from-to)626-639
Number of pages14
JournalRevista Colombiana de Ciencias Químico-Farmacéuticas
Volume52
Issue number2
DOIs
StatePublished - 2023

Keywords

  • Caries
  • Cárie
  • biofilme dental
  • biopelícula dental
  • dental biofilm
  • enjuagues orales
  • enxaguantes bucais
  • mouthwashes

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