Cellular location of KMP-11 protein in Trypanosoma rangeli

Hugo Diez; Ladys Sarmiento; María Leonor Caldas; Marleny Montilla; María Del Carmen Thomas; Manuel Carlos Lopez; Concepción Puerta

doi:10.1089/vbz.2006.0650

Cellular location of KMP-11 protein in Trypanosoma rangeli

Hugo Diez
, Ladys Sarmiento
, María Leonor Caldas
, Marleny Montilla
, María Del Carmen Thomas
, Manuel Carlos Lopez
, Concepción Puerta

Department of Microbiology

Instituto Nacional de Salud
Consejo Sup. de Investigacions Cie.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

We describe the localization of the KMP-11 protein in the Trypanosoma rangeli parasite determined by immunoelectron microscopy using a monoclonal antibody generated against the Trypanosoma cruzi KMP-11 protein. The data reported herein show that the T. rangeli KMP-11 protein is mainly accumulated in the parasite cytoplasm, the coat, the flagellum, and the flagellar pocket. The high degree of sequence homology between the KMP-11 proteins from both parasites suggests that the KMP-11 protein from T. rangeli, like that of T. cruzi, could also be associated with the parasite cytoskeleton.

Original language	English
Pages (from-to)	93-96
Number of pages	4
Journal	Vector-Borne and Zoonotic Diseases
Volume	8
Issue number	1
DOIs	https://doi.org/10.1089/vbz.2006.0650
State	Published - 01 Feb 2008

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Immunoelectron microscopy
KMP-11 protein
Kinetoplastid parasites
Trypanosoma cruzi
Trypanosoma rangeli

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10.1089/vbz.2006.0650

Cite this

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title = "Cellular location of KMP-11 protein in Trypanosoma rangeli",

abstract = "We describe the localization of the KMP-11 protein in the Trypanosoma rangeli parasite determined by immunoelectron microscopy using a monoclonal antibody generated against the Trypanosoma cruzi KMP-11 protein. The data reported herein show that the T. rangeli KMP-11 protein is mainly accumulated in the parasite cytoplasm, the coat, the flagellum, and the flagellar pocket. The high degree of sequence homology between the KMP-11 proteins from both parasites suggests that the KMP-11 protein from T. rangeli, like that of T. cruzi, could also be associated with the parasite cytoskeleton.",

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doi = "10.1089/vbz.2006.0650",

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T1 - Cellular location of KMP-11 protein in Trypanosoma rangeli

AU - Diez, Hugo

AU - Sarmiento, Ladys

AU - Caldas, María Leonor

AU - Montilla, Marleny

AU - Thomas, María Del Carmen

AU - Lopez, Manuel Carlos

AU - Puerta, Concepción

PY - 2008/2/1

Y1 - 2008/2/1

N2 - We describe the localization of the KMP-11 protein in the Trypanosoma rangeli parasite determined by immunoelectron microscopy using a monoclonal antibody generated against the Trypanosoma cruzi KMP-11 protein. The data reported herein show that the T. rangeli KMP-11 protein is mainly accumulated in the parasite cytoplasm, the coat, the flagellum, and the flagellar pocket. The high degree of sequence homology between the KMP-11 proteins from both parasites suggests that the KMP-11 protein from T. rangeli, like that of T. cruzi, could also be associated with the parasite cytoskeleton.

AB - We describe the localization of the KMP-11 protein in the Trypanosoma rangeli parasite determined by immunoelectron microscopy using a monoclonal antibody generated against the Trypanosoma cruzi KMP-11 protein. The data reported herein show that the T. rangeli KMP-11 protein is mainly accumulated in the parasite cytoplasm, the coat, the flagellum, and the flagellar pocket. The high degree of sequence homology between the KMP-11 proteins from both parasites suggests that the KMP-11 protein from T. rangeli, like that of T. cruzi, could also be associated with the parasite cytoskeleton.

KW - Immunoelectron microscopy

KW - KMP-11 protein

KW - Kinetoplastid parasites

KW - Trypanosoma cruzi

KW - Trypanosoma rangeli

UR - https://www.scopus.com/pages/publications/39449130442

U2 - 10.1089/vbz.2006.0650

DO - 10.1089/vbz.2006.0650

M3 - Article

C2 - 18171105

AN - SCOPUS:39449130442

SN - 1530-3667

VL - 8

SP - 93

EP - 96

JO - Vector-Borne and Zoonotic Diseases

JF - Vector-Borne and Zoonotic Diseases

IS - 1

ER -

Cellular location of KMP-11 protein in Trypanosoma rangeli

Abstract

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Keywords

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