@inbook{98e93bf1475646b08befc0ac135c5407,
title = "CD8+ T cell response to trypanosoma cruzi antigens during chronic chagas disease",
abstract = "Flow cytometry is a valuable technique in cellular immunology that allows evaluating effective parameters of the immune response associated with CD8+ T cells. During Chagas disease, infection caused by Trypanosoma cruzi parasite, similar to other intracellular infectious agents, antigen-specific CD8+ T cells are essential for controlling the infection. However, CD8+ T cell response is only partially effective in some chronic Chagas disease patients. Thus, characterization and phenotyping of T. cruzi-specific CD8+ T cells are of great importance during chronic Chagas disease.",
keywords = "CD8 T cells, Chagas disease, Cytometry, Inhibitory receptors, Phenotype, Polyfunctionality",
author = "Paola Lasso and Jose Mateus and Gonz{\'a}lez, {John Mario} and Adriana Cu{\'e}llar and Concepci{\'o}n Puerta",
note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media, LLC, part of Springer Nature 2019.",
year = "2019",
doi = "10.1007/978-1-4939-9148-8_26",
language = "English",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "349--361",
booktitle = "Methods in Molecular Biology",
}